It monitors fetus development & detects its risk of developing chromosomal issues.
Also known as: Dual Marker, 1st Trimester Screening, Maternal Screening, DMT Test for Pregnancy
Blood
You will Save ₹751 on this Test
1.Submit the ultrasound report (NT/NB or Level 1 Scan) during sample collection, ideally between 11-13 weeks + 6 days gestation.
2.Provide maternal details: DOB, weight, LMP/Ultrasound Date, diabetes, smoking, sample date, fetuses (single/twin), conception type (natural/IVF), and Trisomy 21 history if any.
3.Ultrasound report must include scan date, NT, and CRL in mm. Have all information ready before sample collection.
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Double Marker (2)
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Why take double marker test?
What are the benefits of double marker test?
Helps you know your test better
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During pregnancy, parents want to know everything happening inside the womb, if their child is doing ok or not, and what developmental stages the child has gone through already. As the fetus develops, there are chances that there might be some chromosomal abnormalities that the fetus has developed during the period. It is important to ensure everything is ok with the fetus, for the same reason your gynecologist suggests that you get the double marker test done done from the 9th to the 13th weeks of pregnancy. However, the ideal time to assess combined risk is the 11th to 13th weeks of pregnancy.
Double or Dual Marker Test is a blood test that is known as the maternal serum screening test; this test aims to determine if there are any abnormalities in the fetus. This test involves two markers: the beta HCG (human gonadotropin hormone) test and the PAPP-A (pregnancy-associated plasma protein A) Test. If abnormal amounts of these markers are present in the body, there are chances that the fetus might have some chromosomal abnormalities.
When your doctor has suggested that you get the dual marker test, you can opt for Redcliffe Labs and avail of the home sample collection service to collect the blood sample from the comfort of your home.
Also Known As | Double Marker Test, Dual Marker Test, Maternal Serum Screening |
Purpose | Determine if there are any chromosomal abnormalities in the fetus |
Preparation | Refrain from drinking alcohol or smoking before the test |
Fasting | No Fasting Required |
Get Reports Within | 3 Days |
Double Marker Test Cost | INR 2149 - INR 2400 |
Doctors suggest the double-marker blood test when the woman is pregnant to determine if there are any abnormalities in the fetus. However, there are cases where the female cannot skip getting this test done, or it may be risky for the baby.
If you fall into any of these categories, you need to get the double marker test during pregnancy, as it helps give assurance that the baby is healthy.
The double marker test helps determine any abnormalities in the fetus. During the first trimester, the double marker blood test or maternal serum screening can report the likelihood of chromosomal abnormalities. Redcliffe Labs offers the double marker test price at INR 2249, which monitors fetus development and the underlying risks of developing chromosomal issues.
The double-marker blood test can be used to detect abnormalities. There are other uses as well.
The double marker test measures the levels of beta-human chorionic gonadotropin (beta-hCG) and pregnancy-related plasma protein A (PAPP-A) in the blood. Studies prove that hCG and PAPP-A levels are atypical in chromosomally defective pregnancies, where the test can detect these abnormalities and prevent Down’s syndrome.
All three trimesters of pregnancy are crucial. Your doctor may recommend the double marker test to prevent difficulties before and after delivery. The test detects pregnancy-related proteins present in the blood.
If you are 35 or above, they might perform the test to check potential risks of chromosomal abnormalities, especially with family history. However, the test results completely depend on your medical condition, history, and situation.
A pregnant woman needs the double marker test to know your baby's overall health.
During normal pregnancy, the female fetus consists of 22 XX chromosomes and 22 XY chromosomes, and the dual marker test is recommended to determine if the fetus has these many chromosomes or if there is any abnormality. Some of the genetic or chromosomal abnormalities that can be diagnosed through this blood test are:
These genetic conditions can be determined through the double-checker test, and knowing any conditions helps the parents be prepared beforehand.
There is no special set of rules that are to be followed before taking the dual-marker blood test. However, these are some basic guidelines to be followed:
If you follow these basic guidelines before taking the test and keep your physician in the loop, you are ready.
This double marker test is like any other blood test, so the procedure followed is the same.
Remember that the punctured area may have a stinging sensation for around two days. If it lasts more than two days or the pain is significantly severe, you should consult a doctor.
The double marker is a normal blood test doctors suggest for females during pregnancy. As the test helps in determining if the fetus has any chromosomal defects or not, it is one of the important tests your doctor recommends during pregnancy, so it is always suggested that you get yourself tested. Along with getting tested, you must know about the double marker test results, as it gives you an understanding of your reports when they come in. This helps you make important health decisions for yourself and your child.
When the dual marker test is done, it measures two parameters, i.e., the HCG value and the PAPP-A value. The normal HCG value for a pregnant female across all age groups is 25700 to 288000 mIU/ml, and the normal PAPP-A test for females is 1 MoM (multiples of median) across any age group.
For better understanding, the dual marker test results can be divided into two categories:
This is when the test results for both the hormones (HCG and PAPP-A) are in the normal range of 25700 to 288000 mIU/ml for HCG and PAPP-A for 1 MoM. High-
This is considered when the hormone levels vary extremely from normal. The abnormal levels are just an indicator of any abnormality. Still, they do not give any confirmation, so you must consult with your health provider as soon as possible so they can suggest all the tests you need to take further.
Disorder | Screen positive cut-off (ACOG, 2007) | MOM Cut off(ACOG 2007) |
Trisomy-21 | 1:250 | Free BHCG: > or = 1.98 PAPPa:< or = 0.43 |
Trisomy-18/Trisomy-13 | 1:100 | Free BHCG: < or = 0.5 PAPPa: < or = 0.4 |
The Double marker test in pregnancy evaluates the risk of chromosomal abnormalities in a fetus, such as Down syndrome (Trisomy 21) and Edwards Syndrome (Trisomy 18). Follow-up tests are crucial-
The Double Marker Test has multiple advantages for to-be parents:
The ideal time to perform the test is between the 11th and 13th week of pregnancy. Doctors usually perform double-marker blood tests along with a Nuchal Translucency (NT) scan, which checks fluid under the back skin of the fetus’ neck. The test results indicate low, normal, or high risks. High risks don’t necessarily mean chromosomal abnormality.
The test detects Beta hCG and PAPP-A. Beta hCG is 25,700-288,000 IU/ml for every age, while PAPP-A is 1 MoM.
The values of double marker test results indicate whether your baby is at a low, moderate, or high risk for developing chromosomal abnormalities or mental challenges.
If a double market test report shows a low-risk result, it is considered a normal outcome. This means that the risk of chromosomal abnormalities in the fetus is low. It is called a screen-negative result.
If a double marker test report shows positive results, it may indicate a moderate or high-risk pregnancy. Hence, further testing, such as non-invasive prenatal testing (NIPT), may be needed to confirm the diagnosis.
Risk | Normal HCG values | Inference |
Low risk/screen negative | HCG level is between 25700-288000 mIU/mL PAPP level-A is more than or equal to 0.5 MOM. |
These values are closer to normal, which makes the chromosomal defect in the baby unlikely. |
Moderate to high/screen positive | Ratio is between 1:10 and 1:250 | A doctor may suggest more definitive tests to confirm the diagnosis. When the mother is in a high-risk category, it increases the chances of developing chromosomal abnormalities in an unborn child. Nonetheless, if a mother tests positive and continues with the pregnancy, it can increase the risk of death during delivery. |
performed during pregnancy to check for genetic disorders, if any. Going by their names, a double marker test examines two hormones, while the triple marker test examines three hormones. A double marker test is performed within 13 weeks, and a triple marker test is performed after 13 weeks of pregnancy. The double marker blood test measures two substances, specifically hCG and PAPP-A, while the triple marker test measures three substances, specifically AFP, hCG, and estriol.
A triple marker test is considered more accurate than a double marker test. It provides additional information to help assess the risk of fetal abnormalities.
A positive result from either test does not confirm that the fetus has a genetic condition to be screened. Additional testing, such as amniocentesis, may be needed for a definitive diagnosis.
Redcliffe Labs offers affordable double and triple marker tests. Whether your doctor suggests one or the other, you can book a test from us. The double marker test costs INR 2249, which is reasonable and affordable for everyone.
The Double marker test for pregnancy is a simple blood test without risks to the mother or the baby. Here are some factors you should consider before the test:
Misinterpreted results may lead to unnecessary anxiety or additional invasive tests, such as Amniocentesis, which carry a slight risk of miscarriage.
Here is a similarity and difference between the double marker test and NT scan:
A double marker test checks two hormones: hCG and pregnancy-associated plasma protein-A (PAPP-A). The test results are measured in nanograms per milliliter (ng/mL) and milli-international units per milliliter (mIU/mL). The respect is that a test can measure your body's neck, nasal bones, and heart defects in millimeters.
If you don’t want your child to face any chromosomal abnormalities, then it is important to take all the preventive measures from the beginning of the pregnancy. Your doctor may give you advice, depending on your health condition. However, here are a few generic tips that would be beneficial for anyone pregnant:
These are a few things one can do to avoid any birth defects during their pregnancy. However, it would help if you always kept in mind that it is important to take a doctor’s opinion before changing anything in your lifestyle or dietary habits; they will suggest things based on your individual medical history.
The double-marker test at Redcliffe Labs is available for a reasonable price range between 2149 and 2400. This price varies from lab to lab, but we at Redcliffe Labs try to keep the prices as reasonable as possible. You can get your test done in the comfort of your home from the ISO-certified and NABL-accredited Diagnostic Lab, trusted and recommended by many health providers.
If you are looking for a place to get tested, you can contact Redcliffe Labs and avail of the doorstep sample collection service. You get the sample collected from the comfort of your home and get the reports in a stipulated timeframe
City Name | Discounted Price |
Delhi | ₹2249 |
Noida | ₹2249 |
Mumbai | ₹2249 |
Bangalore | ₹2249 |
Kolkata | ₹2149 |
Pune | ₹2249 |
Lucknow | ₹2400 |
Ahmedabad | ₹2249 |
Hyderabad | ₹2249 |
Chennai | ₹2249 |
Gurgaon | ₹2249 |
Jaipur | ₹2400 |
Faridabad | ₹2249 |
Indore | ₹2400 |
Patna | ₹2400 |
Tests/Packages | Offer Price in INR |
HCG Test | ₹499 |
HCG Tumor Marker (Cancer) Test | ₹650 |
Alpha Fetoprotein (AFP), Maternal Marker Test | ₹900 |
Pregnancy Associated Plasma Protein-A(PAPP-A) Test | ₹1000 |
Double Marker Test- Auto-Delfia | ₹2500 |
Double Marker Test + PLGF- Roche | ₹3200 |
Triple Marker Test | ₹2799 |
Quadruple Marker Test | ₹3600 |
The factors that can affect the double marker test results include:
The double marker test is a valuable tool for assessing the risk of chromosomal abnormalities in the developing baby. These may include Down syndrome, Edward syndrome, and Patau syndrome. The test is performed during the first trimester of pregnancy. Early screening can help ensure that parents know their unborn baby is growing healthily. Additionally, early detection can lead to timely intervention, minimizing the risk of complications.
The test provides peace of mind to expecting parents, especially those who are anxious about knowing the child’s growth inside the fetus. Consult your healthcare provider about this test, as his guidance will provide a comprehensive understanding, and if suggested, you can experience a healthy pregnancy.
You will Save ₹751 on this Test
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