Sex Hormone Binding Globulin (SHBG) Test - Price, Purpose

Table of Content

Introduction to SHBG Test

The Sex Hormone Binding Globulin (SHBG) measures the levels of SHBG in a blood sample. SHBG is a protein that binds to sex hormones in your blood. SHBG testing provides details about the working of testosterone in the body. Your doctor may suggest the SHBG test if you have symptoms suggestive of having too much or too little of the sex hormone testosterone. Testosterones are “male” sex hormones. In females, they are present in smaller amounts. 

Sex hormone-binding globulin (SHBG) levels are different in every individual. Factors such as sex, age, weight, genetics, and metabolism impact your normal levels of SHBG. Your healthcare provider may suggest a SHBG blood test if he suspects your testosterone levels are abnormal. For males, testosterone levels are too low. In females, the levels may be high. 

If your doctor has suggested an SHBG blood test, suspecting you have abnormal testosterone levels, you need not delay. Book the SHBG test from Redcliffe Labs now! Avail of the home sample collection service. Our phlebotomist will arrive at your place at the given time and get accurate reports within 36 hours. 

Test details in brief

What is the purpose of the SHBG test?

The SHBG blood test is usually recommended to check low testosterone in men. The test is also suggested to evaluate women with signs and symptoms showing excess male hormones. If you are a male, you may need an SHBG test if you have the following symptoms: 

• Low sex drive
• Difficulty getting an action
• Fertility Problems. 

In females, the test is usually recommended if they have symptoms of high testosterone, including: 

• Excessive hair growth on the face and body
• Change in voice
• Irregular or no periods at all
• Acne
• Weight gain
• Fertility issues

The test can help in the following ways: 

• Assessment of hormone imbalances: The SHBG test can help detect conditions responsible for hormonal imbalances, such as polycystic ovary syndrome (PCOS), hirsutism, and hypogonadism. Early detection can help in treatment planning and avoiding negative outcomes. 
• Evaluation of androgen-related disorders: Your SHBG levels might be affected if you have hyperthyroidism or liver disease. Hence, the doctor may suggest a test to determine the blood's FAI or amount of androgen. 
• Monitoring hormone replacement therapy: In the case of transgender people who are undergoing hormone replacement therapy (HRI), the SHBG test can help in determining the effectiveness of treatment and dosage adjustments. 

The SHBG levels play an integral role in hormonal regulation, helping to diagnose and manage various conditions related to sex hormone imbalances. 

What does the SHBG test detect?

The SHBG test helps evaluate men with low testosterone levels and females with excess testosterone production. SHBG is a protein that carries estrogen, dihydrotestosterone (DHT), and testosterone throughout your blood. Too little testosterone in males and excess testosterone in females can cause problems. The SHBG test accurately measures the bound and unbound levels of these sex hormones. 

SHBG levels tend to change, so your healthcare provider may also test total and free cholesterol blood levels to confirm androgen deficiency. 

How can you prepare for the SHBG test?

The SHBG test doesn’t need special preparation, but remembering a few things before the test will help you get accurate SHBG test results. 

• No fasting is required: You can eat your normal food and drink water before the SHBG test. 
• Avoid medications: SHBG testing is crucial for detecting abnormal testosterone levels in males and females. Consult your healthcare provider if you need to continue or stop taking your prescription medicine to avoid interfering with the test results. 

Feel free to discuss doubts or concerns regarding the SHBG test to improve the accuracy of test results. 

What is the procedure for the SHBG test?

The SHBG blood test is simple and takes less than five minutes. The procedure involves the following steps: Have a look below. 

• After booking the SHBG blood test with us, our phlebotomist will come to your house at the given time. He will carry a home blood sample collection kit to collect your SHBG blood sample. 
• The phlebotomist will look for a suitable vein in your arm and insert a needle to draw a small amount of blood. 
• After drawing the blood from your vein, he will transfer it into a vial or test tube and label it. 
• This sample will be sent to a laboratory, where experts will analyze it. The reports will then be prepared. 

What do the test reports indicate?

The SHBG test results can indicate normal, high, and low SHBG levels. The normal ranges for SHBG concentrations in adults are: 

• In females (non-pregnant females) between 18 and 144 nmo/L
• In males, between 10-57 nmol/L. 

If your SHBG levels are high, it indicates potentially lower levels of free sex hormones for your body to use. 

In men, too many free testosterone levels can cause: 

1. Fluid retention
2. Acne on the face 
3. Increase in appetite and weight gain
4. Muscle mass increases
5. Mood swings
6. Difficulty getting and keeping an erection
7. Breast size increases 

In females, excessive free testosterone can result in

1. Weight gain
2. Hair growth on the face and body
3. Acne 
4. Menstrual changes
5. Breast tenderness
6. Bloating
7. Mood swings. 

The increased SHBG levels may be seen in individuals with: 

1. Liver disease 
2. Overactive thyroid (hyperthyroidism)
3. Eating disorders
4. Pregnancy 
5. Hypogonadism (decreased sex production in men) 
6. Low testosterone 

Low SHBG levels mean more free and active hormones circulate in the bloodstream, causing several health issues: 

Common symptoms in men are: 

1. Decreased libido
2. Reduced energy
3. Potential erectile dysfunction
4. Low sperm count
5. Bone less
6. Increase in body fat. 

Common symptoms in women are: 

1. Vaginal dryness
2. Depression or anxiety
3. Loss of strength and muscle tone
4. Lack of energy and tired 
5. Thinning hair 
6. Trouble conceiving 

The decreased SHBG levels are related to the following: 

1. Obesity
2. Polycystic ovary syndrome (PCOS)
3. Underactive thyroid
4. Excess Androgen
5. Type 2 disease 
6. Metabolic syndrome
7. Excessive use of glucocorticoids 

Note: Discuss your SHBG test reports with your healthcare provider. Do not hesitate to ask important questions, including treatment, for better outcomes. 

Who should take the SHBG test?

 The SHBG test is useful for certain individuals: 

• Men with low testosterone include reduced libido, fatigue, or muscle loss. The test can help assess whether low testosterone is due to high SHBG levels. 
• Women with symptoms of hormonal imbalance such as irregular menstrual cycles, severe acne, or excessive hair growth. The test helps determine if hormonal imbalances are contributing to these issues. 
• Individuals with suspected liver disease can help assess liver function or monitor the progression of liver disease. 
• People with thyroid disorders. The test is useful for such individuals to understand their hormonal status better. 
• Those with unexplained infertility should take the test to get insightful information about hormonal balance. 
• Patients on hormone therapy or hormonal treatment should take the test to know how well the therapy is working. 

What if the SHBG test reports are positive?

If your SHBG test reports show elevated or positive SHBG levels, it can affect the balance of sex hormones. 

Causes of High SHBG levels: 

• Hyperthyroidism can lead to high SHBG levels. 
• Liver disease can increase the production of SHBG. 
• Estrogen therapy includes hormonal treatments, and especially estrogen can cause an increase. 
• Aging: As you age, SHBG levels tend to increase naturally. 
• Low testosterone: In men, high SHBG levels often correlate with lower, free testosterone. 
• Certain medications, such as oral contraceptives and anticonvulsants, can increase SHBG levels. 

Symptoms of high SHBG levels: 

• In men: fatigue, reduced muscle mass, low libido, and erectile dysfunction. 
• In females: mood changes, fatigue, and irregular periods. 

What are the risk factors associated with the SHBG blood test?

There are no major risks associated with the SHBG blood test. However, like any blood test, there are minor risks, such as pain or discomfort and bruising on the puncture site. Although there are rare chances of infection, swelling, or excessive pain at the needle site, immediate medical attention is advisable. 

Some people may feel lightheaded or faint during or after the blood test, especially if they have a fear of needles. 

What are normal SHBG levels for men and women?

The normal SHBG levels differ between men and women and vary with age and other factors. 

Men: 

• In adult men: 10 to 57 nmo/L

Women: 

• In premenopausal women: 18 to 144 nmo/L
• In postmenopausal women: 16.8 to 125.2 nmol/L. 

How can you increase SHBG levels?

You can increase your SHBG levels by adopting some natural and medical approaches to raise SHBG levels: 

1. Exercise regularly: Engage in regular physical activity, such as walking, running, and cycling. 
2. Limit sugar and carbs intake: Focus on a diet rich in whole grains, vegetables, and low-sugar fruits. 
3. Eat a balanced diet: Incorporate foods that promote hormone balance, such as: 
4. High-fiber foods: whole grains, vegetables, and fruits
5. Protein-rich foods: lean meats, legumes, and nuts. 
6. Healthy fats: Omega-3 fatty acids from flaxseeds, fish, and walnuts. 

Any additional points about the SHBG test that might be useful: 

Some more tests may be ordered with the SHBG blood test to help diagnose early puberty in children. The levels of SHBG are normally high in all children. The high SHBG levels in children prevent sex hormones from affecting the body tissues. However, the low SHBG levels in children may start puberty too early. 

Book the SHBG test from Redcliffe Labs at INR 2500. 

If your doctor has suggested the test for assessing hormonal imbalances, you need not delay. You can download the Redcliffe mobile app or call us directly to book an appointment. The SHBG test price at Redcliffe Labs is INR 2500. You can also use our express slot booking facility to pick up your sample within 45 minutes. Get your SHBG test reports within 36 hours. 

Healthy India Ki trusted Redcliffe Labs, which specializes in comprehensive pathology services, including blood testing. With a team of skilled phlebotomists for at-home sample collection, Redcliffe Labs ensures precise and reliable test results, allowing every individual to manage their health effectively. 

Sex Hormone Binding Globulin (SHBG) Test Cost in Different Cities - Redcliffe Labs

Note: We also offer Sex Hormone Binding Globulin (SHBG) Test PAN India. Please call the number 8988988787 to check the availability of our services in your area.

Conclusion

In conclusion, the SHBG (sex hormone-binding globulin) test provides valuable information about the binding and availability of sex hormones in the bloodstream. Elevated or decreased SHBG levels can indicate various underlying health conditions. Consult a doctor to understand what SHBG levels mean for your specific situation and determine any necessary follow-up actions or treatment.