C-reactive protein (CRP) is a blood marker for inflammation produced by the liver. A simple blood test measures the level of CRP in your body. The test helps diagnose acute and chronic conditions that lead to inflammation in the body. In this article, you will learn about the normal range of CRP, CRP levels in COVID-19 patients and ways to control your CRP levels.

Acute or chronic inflammation in the body could be a response against multiple diseases, including viral infections like Covid-19. Look out for signs like abdominal pain, fatigue, chest pain, mouth sores, or joint pain. Symptoms like these indicate a possibility of inflammation in the body. Getting a CRP test allows you to get a confirmation and treatment to treat it on time.


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Normal Range of CRP Levels

In a healthy adult, a CRP value less than 3 mg/L is considered normal. The CRP values above 3 mg/L may indicate inflammation. Different levels of CRP and their indications are tabulated below: 

S.No. CRP Level  Inference  Description
1. < 3 mg/L Normal  Indicates healthy adults
2. 3 mg/L – 10 mg/L Normal or minor elevation Observed in pregnant women or people with diabetes, depression, obesity, sedentary lifestyle, or smoking. It may also indicate the risk of cardiovascular diseases.
3. 10 mg/L – 100 mg/L Moderate elevation Observed in people with cancer, autoimmune disease, heart attack, and bronchitis.
4. 100 mg/L – 500 mg/L Marked elevation Observed in people with acute bacterial infection, viral infection, or trauma.
5. > 500 mg/L Severe elevation Acute bacterial infection

High Sensitivity CRP (hsCRP)

A high sensitivity CRP (hsCRP) test is conducted to appropriately detect the levels of CRP that are below 10 mg/L. The hsCRP test is generally recommended if you are at a higher risk of heart disease. The level of CRP in hs-CRP and their respective inferences are tabulated below:

S.No. hs-CRP level (mg/L) Inference 
1. < 1.0  Low risk of heart disease
2. 1.0 – 3.0 Moderate risk of heart disease
3. 3.0 – 10.0 High risk of heart disease

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CRP Levels in COVID-19

C-reactive protein is an essential biomarker in COVID-19 patients. This may be due to the overproduction of inflammatory cytokines during the infection. Higher levels of CRP were observed in patients with low oxygen saturation (< 90%) as compared to those with high oxygen saturation (> 90%). According to research studies, the levels of CRP in different groups of COVID-19 patients are tabulated below:

S.No. Patient Group CRP Level (mg/L)
1. Hospitalized  47.651.4
2. Death  100 – 113
3. Recovered  9.6 – 26.2
4. Admitted to the ICU with GI symptoms and without GI symptoms 15.7 and

7.9

5. Admitted to the ICU  43.162.9
6. Mild 7.6 – 23
7. Non-severe  10 – 12.1

Ways to Reduce CRP Levels

With certain modifications in your diet and lifestyle, you can control your CRP levels. Certain steps that you can take to reduce your CRP levels are

  • Weight loss: According to a study, decreasing the total body weight and fat mass by 5% can cause an effective decrease in the CRP levels.
  • Optimistic approach: According to a study, having a negative mindset leads to increased CRP levels.
  • Exercise: Daily exercise and an active lifestyle are essential to maintain an optimum level of CRP.
  • Treat the underlying cause: To decrease the level of CRP, you need to target and treat the underlying disorder responsible for the elevated levels of CRP.
  • Diet: Including food items like apples, bananas, avocados, beans, broccoli, sprouts, legumes, strawberry, pear, and whole grains can help manage CRP levels.
  • Supplements and medicines can also reduce CRP levels in your blood. These should be taken only when prescribed by a registered medical doctor.

Takeaway 

CRP levels are a key indicator of your health and help diagnose any inflammation or infection. However, it is important to note that increased CRP levels may not tell the exact site of inflammation or infection, and other diagnostic investigations may be required for the same. The levels of CRP reduce as the inflammation is treated. Hence, it serves as a very important prognostic marker. Lifestyle modifications also aid in decreasing the levels of CRP. You can better analyze your laboratory blood test reports now that you know about the normal CRP levels and what they indicate. 

Frequently Asked Questions (FAQs)

  • What does the CRP level of 50 mg/L indicate?

In most cases, a CRP level of 50 mg/L or more indicates the existence of a bacterial infection in your body.

  • What is the CRP level in COVID-19?

The level of CRP in COVID-19 patients depends largely on the severity of the condition. Usually, the CRP levels in COVID-19 patients vary from 20 mg/L to 50 mg/L.

  • How can I get my CRP levels tested?

You can get your CRP level tested by a simple blood test. You can easily book a CRP blood test at Redcliffe labs from our official website or by calling our dedicated helpline number. Our phlebotomist will visit your place and collect your blood sample for the test at no added charge.

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Prekshi Garg is a young, dynamic, energetic, and meritorious professional biotechnologist. She is a merit rank holder in her post-graduation and a skilled bioinformatician with great zeal to do her best in neurosciences. She is currently working in the area of Neurotranscritomics dealing with neurodevelopmental and neurodegenerative disorders. She has presented many papers at different scientific forums and is awarded ‘Representing the Institution in Scientific Events’ citation by Amity University Uttar Pradesh and Top position in Student Assistantship Program held at Amity University in addition to awards won for oral presentations in different scientific deliberations. Prekshi has published a good number of papers and book chapters during the start of her academic career itself. Her tremendous skills and knowledge make her a good blend of biotechnology and bioinformatics.

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