The liver is a crucial organ in the human body, and  is responsible for handling various metabolic functions in the body. One of the most important roles of the liver is to detoxify the blood by processing different waste products in the hemoglobin. To conduct all of these functions properly, the liver produces and secretes several types of enzymes for optimal regulation. SGOT (Serum glutamic oxaloacetic transaminase) and SGPT (Serum glutamate pyruvate transaminase) are two of the most common enzymes produced by the liver. SGPT test, or Serum Glutamic Pyruvic Transaminase, is a blood test that can be used to detect any liver problems. It is commonly used to measure the level of a specific enzyme called ALT (alanine aminotransferase), a specific enzyme that is released when the liver is damaged or inflamed. If a patient has a high level of ALT, it may indicate that his liver has been damaged. However, if the results are at the SGOT test normal range then it is usually a sign that his liver is functioning properly.

Our liver partakes in several physiological functions. Experiencing vomiting, nausea, fatigue, leg swelling, jaundice, excessive bleeding or bruising could be an early sign of liver dysfunction. Don’t brush these alarming symptoms under the rug. Instead, consult a doctor and get tested without any delay. Make the right decision today for a healthier tomorrow.

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In this article, we will explore more about SGPT, SGOT, and their significance in liver function. We will also discuss the test results, their interpretation, and what they mean for your liver health.

What is SGPT and SGOT?

SGPT and SGOT are two of the most common types of liver enzymes. When liver cells are damaged or inflamed, these enzymes can leak into the bloodstream, causing elevated levels of SGOT and SGPT in a blood test. As a result, these enzymes are commonly used as markers of liver function and can help diagnose liver diseases such as hepatitis, cirrhosis, or liver cancer. Besides the liver, SGOT is found in the kidney, muscles, heart and even the brain. On the contrary, SGPT is predominantly found in the liver only. Elevated levels of either of the enzymes can result from:
  • SGOT levels can rise during liver complications, heart attacks or muscle injuries.
  • SGPT levels can rise during liver diseases and damage to the tissues in the liver.
However, elevated levels of SGOT and SGPT can also be caused by other factors such as alcohol consumption, certain medications, or muscle damage. The SGPT levels are more inclined towards determining liver diseases and damage due to its elevated levels.

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What are the symptoms of elevated SGPT and SGOT levels?

If you see a doctor with the following symptoms, they might suggest undergoing the SGPT & SGOT tests. However, in most cases, elevated SGOT and SGPT levels may not cause any noticeable symptoms. Some people may experience mild symptoms such as –
  • Constant feelings of fatigue and tiredness
  • Vomiting and nausea
  • Abdominal discomfort
  • Bruising quickly
In more severe cases, liver disease can cause symptoms such as –
  • Jaundice
  • Shortness of breath
  • Swelling in the leg
  • Swelling in abdomen
  • Dark urine
  • Pale stools
Experiencing these symptoms is a warning sign that you need immediate medical intervention. If the test reports come back with high SGOT and SGPT levels, your doctor will move ahead with further testing or proceed with the treatment.

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How is the SGPT/SGOT Blood test is Performed?

The SGPT test is performed by obtaining a blood sample from a vein in the arm. This sample is then analyzed by a qualified technician at a laboratory. A test report is then generated, which will provide the results in units per liter of blood. The test results are useful in detecting liver diseases and in diagnosing hepatitis. It is also used in monitoring the effects of medicines that may damage the liver. It is a painless procedure and does not require special preparation. Typically, the test can be performed within five minutes. Your doctor will prescribe getting an SGPT & SGOT test to analyze your liver function and rule out possible complications.

What are normal levels of AST (SGOT) and ALT (SGPT)?

The SGPT and SGOT test normal range are standard. However, the range can slightly vary, depending on the testing method in the laboratory.
  • Normal SGOT levels – 5 to 40 units per liter of serum
  • Normal SGPT levels – 7 to 56 units per liter of serum
If the blood test reports are drastically different than the normal range, it can signify potent complications in the body, especially with liver diseases and disorders.

What do Elevated SGPT and SGOT levels Indicate?

Since SGPT and SGOT are quintessential enzymes produced in the liver, it isn’t surprising that altered levels of these enzymes indicate signs of liver damage. The high levels are often indicative of several underlying complications in the body such as viral hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, cirrhosis, or liver cancer. However, elevated SGPT and SGOT levels can also be caused by other factors such as certain medications, strenuous exercise, or muscle damage. Therefore, it is important to consult with a healthcare provider to determine the underlying cause of elevated SGPT and SGOT levels. Regular monitoring of liver enzymes can also help to detect liver disease early and prevent long-term liver damage.

Are SGPT and SGOT Indicative of Liver Disease only?

As we mentioned, that isn’t the case at all. Lower or elevated SGPT and SGOT enzymes aren’t just tied with liver disease or liver function. Sometimes, patients with elevated levels of these two enzymes have optimal liver function. 

How can I prepare for the SGPT/SGOT Blood test?

The SGPT/SGOT blood tests are a part of the liver function test and are routine blood test that doesn’t require excessive prepping. The patients don’t have to fast or worry about the day when the blood is drawn. However, for accurate results, we’d recommend discussing the medications you take. Since medications can alter the final reports, your doctor might advise getting the blood drawn before taking the medications. The phlebotomist will collect the blood sample from the veins in your forearm after disinfecting the area. The collected sample is then sent for further testing to the laboratories.

Are there any risks associated with the SGPT/SGOT blood tests?

The SGPT/SGOT assessment in the body is done using a blood test. This means that the risks associated with these routine blood tests are very low and sometimes non-existent. However, in very rare cases, some of the common risks might include:
  • Excessive bleeding at the puncture site
  • Hematoma or clotted blood underneath the skin
  • Feeling lightheaded
  • Infection

What do the Abnormal Test results Indicate?

Abnormal SGPT-SGOT levels in the bloodstream can be indicative of several complications, including:
  • Hepatitis
  • Liver cirrhosis
  • Liver tissue damage
  • Liver cancer
  • Tumor in the liver
  • Obstructed blood flow to the liver
  • Hemochromatosis or iron build-up in the bloodstream
  • Mononucleosis caused by Epstein-Barr virus
  • Pancreatitis
If you have lower SGPT-SGOT levels in the bloodstream, that indicates a healthy liver. Unlike other markers, a low level, in this case, doesn’t signify anything alarming.

What is the cost of the SGPT-SGOT Blood test in India?

The SGPT-SGOT blood test in India typically starts from INR 80 each. The price will vary depending on the city and the laboratory the test is done in.

What is the Alarming Level of SGOT and SGPT?

The normal levels of SGPT usually must lie between 7-56 units/liter of serum. However, if the level of SGPT shows more than 56 units/ liter in the patient’s blood test, then that is referred to as an alarming level.  The normal level of SGOT usually must lie between 8-45 units/ liter of the serum. However, anything above 50 units/liter for men and above 45 units/ liter for women can be considered as alarming. The high levels of SGOT and SGPT often indicate severe underlying complications for the patients.

Takeaway

SGPT and SGOT are key markers of liver function. If your doctor has prescribed these tests, it can indicate that they want to assess the state of your liver function along with other allied physiological functions.  Additionally, with the availability of online booking facilities, you can easily book your test from the comfort of your home with Redcliffe Labs to ensure accurate and reliable results. Regular monitoring of liver enzymes can also help detect liver disease early and prevent long-term liver damage. Overall, taking care of your liver health is crucial for maintaining overall health and well-being.

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Prekshi Garg is a young, dynamic, energetic, and meritorious professional biotechnologist. She is a merit rank holder in her post-graduation and a skilled bioinformatician with great zeal to do her best in neurosciences. She is currently working in the area of Neurotranscritomics dealing with neurodevelopmental and neurodegenerative disorders. She has presented many papers at different scientific forums and is awarded ‘Representing the Institution in Scientific Events’ citation by Amity University Uttar Pradesh and Top position in Student Assistantship Program held at Amity University in addition to awards won for oral presentations in different scientific deliberations. Prekshi has published a good number of papers and book chapters during the start of her academic career itself. Her tremendous skills and knowledge make her a good blend of biotechnology and bioinformatics.

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20 replies on “SGPT & SGOT Test: Normal Range, its levels, and what do they indicate?”

  • Avatar
    Mohammad Abdul Rahiman
    October 13, 2022 at 9:24 am

    Good morning madam
    My sgpt is 54
    I check 2 times coming same readings within 2 weeks

    • Avatar
      October 17, 2022 at 3:27 pm

      Yes it is just normal. But make sure you keep a track of it and do regular checkups

      • Avatar
        Rukhasana kausar
        October 30, 2022 at 1:47 pm

        My blood test repot
        AST-SGOT is 35 U/L.
        Lab reference range is <32 U/L.
        Is this normal report?

    • Avatar
      Amresh kumar Shukla
      October 18, 2022 at 6:23 pm

      My sgot is 52 and sgpt is 117. Do I need treatment?

      • Avatar
        November 3, 2022 at 2:38 pm

        Thank you Amresh for your enquiry. You may ask your query on our health community https://redcliffelabs.com/health-community/ and you would receive an appropriate response and along with that you would also receive more content on liver management on this platform.

  • Avatar
    marvin
    October 18, 2022 at 6:30 pm

    hi! I have a high sgpt and sgot results. sgot-52 sgpt-74. i am 32yrs old and super health concious. i seldom eat fried food, i don’t eat pork, i don’t eat chicken skin, i don’t smoke, i don’t drink alcohol, i eat fruits and vegetables, i drink plenty of water, i don’t drink soda, I sleep well, i exercise, and yet i still get these results every time our company conduct annual medical check up. i was diagnosed of having high cholester too and i don’t have any idea how?

    • Avatar
      November 3, 2022 at 2:30 pm

      Thank you marvin for your enquiry. You may post your enquiry on our health community platform https://redcliffelabs.com/health-community/ and you would receive an appropriate response. you may also read more content around liver management on this platform.

      • Avatar
        Rachit choudhary
        March 7, 2023 at 2:13 pm

        Sir/madem !! Mera SGOT/SPGT 114.9/129.2 Hai
        Kya mera liver khrb ho gya h …. Age 27 years

        • Avatar
          March 16, 2023 at 6:28 pm

          Hi Rachit,

          Avoid oily foods for 2 weeks, again repeat. Stop alcohol if taking.

          Thankyou

  • Avatar
    Bivin Balan
    October 23, 2022 at 3:18 pm

    My sgpt is 98….Is it in danger range?

  • Avatar
    Reejay Duero
    October 26, 2022 at 10:04 am

    Good day, the clinical results of my SGPT – 118 and my SGOT – 129.55. What will do to lower it down?, What medication should I take?

  • Avatar
    Rukhasana kausar
    October 30, 2022 at 1:52 pm

    AST-SGOT report 35 U/L
    Lab ranges is <32
    Is this normal report?

  • Avatar
    Manoj KumarSG
    December 10, 2022 at 11:57 pm

    My SGOT 110 and SGPT 167
    What will do to lower it down

  • Avatar
    Ashkar
    March 10, 2023 at 7:22 pm

    Hello Dr, this is just want to know SGPT 79.20h and SGOT 39.30 is normal ?
    And what i will do for my next step to normal

    • Avatar
      March 14, 2023 at 3:01 pm

      Hi Ashkar,

      Your SGOT levels are normal but SGPT levels are high. Consult a doctor for further diagnosis and treatment.

      Thankyou

  • Avatar
    Genevieve Remiendo
    March 21, 2023 at 5:12 am

    Hi, Good Day!
    My SGPT is 46 and SGOT is 33.. Is this normal?
    What precaution should i need?
    Thank you

    • Avatar
      March 21, 2023 at 12:40 pm

      Hi Genevieve,

      You SGPT and SGOT levels are in normal range.

      Thankyou

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