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GGT Test: Price, Range, Preparation, Results, & More

Lab Test

GGT Test: Price, Range, Preparation 2024

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Medically Reviewed By
Dr. Ragiinii Sharma

Written By Dr Divya Rohra
on Apr 18, 2022

Last Edit Made By Dr Divya Rohra
on Oct 7, 2024

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Gamma-glutamyl-Transferase-(GGT)-Test
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For prolonged symptoms of chronic stomach pain, fatigue, and poor appetite, your doctor may recommend the GGT or Gamma-glutamyl Transferase test. GGT is an essential enzyme found in the body’s cells and tissues, mainly in the liver. 

Test for GGT is a liver function test often done to detect liver diseases and bone disorders. However, the GGT test cannot pinpoint the specific cause of the liver condition. The tests performed with other liver function tests can rule out other medical conditions based on the abnormal test outcomes. 

The test helps to screen for chronic alcohol abuse and to monitor for alcohol use if you are receiving treatment for alcoholism or alcoholic hepatitis.  You can take a GGT blood test at home with Redcliffe Labs; the professional experts will provide you with the best service experience right from home. Our professional phlebotomist will test you within 45 minutes with our express slots.

This article dives into what the GGT is, 

  • When and how it is done, 
  • Normal and abnormal result interpretation, and 
  • Cost of the GGT test in India.

GGT Test Details In Brief:

Also Known AsGamma-Glutamyl Transferase (GGT) or GGT blood test
PurposeThe GGT test analyzes the GGT levels in the blood. The elevated levels can indicate liver damage.
PreparationDo not take any over-the-counter medicine without confirming with your Doctor.
FastingNo Fasting Required
Get Reports WithinWithin 12 hours
CostINR 260

GGT test: What is it?

Gamma-glutamyl transferase (GGT) or gamma-glutamyl transpeptidase is an enzyme found in every cell and tissue of the body. Primarily concentrated in the liver, GGT is involved in all the prime functions of the liver.

A gamma-glutamyl transferase (GGT) blood test or gamma GT test assesses the GGT levels in the blood. When the liver or bile ducts get damaged, GGT may leak into the bloodstream. Thus, elevated levels of GGT in the blood mean that the liver or bile ducts are injured or damaged.  

Typically, the GGT test is highly sensitive for detecting bile and liver problems, as GGT increases even when the liver or bile ducts are slightly blocked or constricted. The GGT levels also spike up when certain medications- phenobarbital, warfarin, etc., are administered and abusive alcohol intake.

However, as many reasons can lead to elevated GGT, the GGT liver function test is usually considered with other liver function tests such as:

  • Alkaline phosphatase (ALP) blood test,
  • Aspartate aminotransferase (AST) blood test,
  • Lactic dehydrogenase (LDH) blood or fluid assay

Purpose of GGT Test

Your doctor may recommend a GGT blood Test if you are suspected of liver damage or have liver disease, especially related to alcohol use. The test is primarily used for the following purposes:

  • Liver Function Assessment: This test commonly assesses liver health and function. However, GGT alone is not specific to any particular liver condition and is usually used with other liver enzymes (e.g., ALT, AST, alkaline phosphatase) to evaluate liver function comprehensively.
  • Detection of Liver Diseases: The elevated GGT level indicates liver diseases such as hepatitis (both acute and chronic), cirrhosis, alcoholic liver disease, and non-alcoholic fatty liver disease (NAFLD).  Monitoring changes in GGT levels over time can help diagnose and manage these conditions.
  • Alcohol Consumption: GGT is particularly sensitive to alcohol-induced liver damage. Chronic alcohol consumption can raise GGT levels before other liver enzyme levels are significantly affected. As a result, the GGT blood test can be used to assess alcohol consumption patterns and identify potential alcohol-related liver problems.

Bile Duct Disorders: GGT is found in the cells lining the bile ducts. Elevated GGT levels may indicate problems with the bile ducts, such as obstruction, inflammation, or other biliary tract disorders.

When is the GGT test done?

The reasons for performing a GGT test can be many, from understanding the possibility of liver damage or bile duct constriction to alcohol hepatitis. The reasons for the test are explained below. 

  • Increased alkaline phosphatase (ALP) level in the blood: ALP increase alone indicates bone disorders. However, elevated ALP and GGT point out liver or bile duct problems. 
  • Symptoms of liver disease or bile duct issues: For symptoms such as;
  • Nausea,
  • Vomiting,
  • Belly (abdominal) pain,
  • Itchy skin,
  • Jaundice- yellowing of the skin, eyes, and nails,
  • Tiredness or fatigue,
  • Loss of appetite, GGT along with ALT, AST, ALP, and bilirubin tests are done to determine the specific liver or bile duct disorder,
  • Screen alcohol use disorder: Alcohol consumption increases the GGT levels in the blood, 
  • Monitor the treatment progress for alcohol abuse: GGT test helps monitor the condition of the liver while undergoing treatment for alcohol use disorder and alcohol hepatitis

How is the GGT test done?

The GGT test is a routinely performed blood test where the lab technician draws a certain amount of blood from the veins of the arms. Medications, supplements, and alcohol consumption can affect the GGT levels. 

Before the test, inform your physician about the medications and other habits. Your doctor will guide you through the process and let you know whether the medications are necessary during the test or not. It is also paramount to avoid alcohol at least 24 hours before the test. 

Preparation for GGT Blood Test

Usually, the GGT Test does not require any special preparation or fasting. The GGT blood test is performed by taking blood samples from the vein in your arm.  However, you must follow some specific instructions before going for the test. 

  • No Fasting: You can eat and drink as usual, as no fasting is required for the GGT blood test. 
  • Time of the day: The GGT test can be performed at any time, but some doctors may prefer to perform the test in the morning as part of a liver function panel.
  • Inform your healthcare provider: Before taking any blood test, inform your healthcare provider about any medications and supplements you are taking. 

Interpretation of GGT test results

The normal range for gamma-glutamyl transferase (GGT) varies between laboratories. The reference range of GGT in adults is 5 to 40 U/L (units per liter). GGT levels are usually higher in men compared to women. Also, In women, the GGT levels increase with increasing age. 

Lower than the reference range of GGT shows less likelihood of having a liver disorder. However, high gamma GT means that the condition in the body is damaging the liver. Though GGT cannot help understand the specific reason for the damage, the higher the GGT, the greater the damage. 

Some of the conditions caused when the gamma-glutamyl transferase levels go high are:  

  • Inflammation of the liver or Hepatitis due to viral infection or abusive alcohol consumption,
  • Liver scarring or Liver Cirrhosis, 
  • Blockage of bile ducts or Liver Cholestasis, 
  • Alcohol liver disease,
  • Non-alcoholic fatty liver disease,
  • Liver tissue damage and death causing obstructed blood flow to the liver- Liver ischemia, 
  • Cancer or tumour in the liver, 
  • Alcohol use disorder or alcohol addiction,
  • Pancreatic cancer or pancreatitis, 
  • Diabetes,
  • Heart failure,
  • Certain medications cause damage to the liver,

GGT blood test report, along with other blood tests, liver function tests, and medical history, is conducted to diagnose the condition and move ahead with the treatment. 

What is the GGT normal range?

The normal range of GGT can vary slightly from one laboratory to another, but generally, the reference range for GGT in adults is around 5 to 30 U/L. These ranges may vary based on age, sex, and the laboratory's specific reference values.

GGT LevelRange
Normal GGT level (Adult)5- 48  U/L
Mild GGT level (Men)55- 138  U/L
Mild GGT level (Women)38 – 95 U/L
Moderate GGT level (Men)138-275 U/L
Moderate GGT level (Women)95 – 190 U/L
Marked GGT level (Men)275- 550 U/L
Marked GGT level (Women)190 – 380 U/L

Risk of Abnormal GGT range

The increased level of GGT indicates health issues related to the liver, bile ducts, or alcohol consumption. Here are some risk factors and implications associated with abnormal levels of GGT.

  • Liver Diseases: The higher level of GGT causes various liver diseases, including hepatitis (both acute and chronic), cirrhosis, Cholestasis, Liver tumor, and fatty liver disease (NAFLD/NASH). Viral infections, excessive alcohol consumption, metabolic disorders, or other factors may cause these conditions.
  • Bile Duct Disorders: GGT levels can be elevated in cases of bile duct obstruction, inflammation (cholangitis), or other biliary tract disorders. 
  • Alcohol Consumption: One of the most common causes of elevated GGT levels is chronic or heavy alcohol consumption. GGT is sensitive to alcohol-induced liver damage, and its levels can rise even before other liver enzymes show significant changes.
  • Medications and Drugs: Some medicines and drugs, including certain pain relievers, anti-seizure medications, and others, can lead to elevated GGT levels.
  • Obesity and Metabolic Syndrome: Obesity and metabolic syndrome are associated with fatty liver disease (NAFLD), which can cause increased GGT levels.

Cardiovascular Risk: Abnormal GGT levels have been associated with an increased risk of Liver conditions that can cause elevated GGT levels, including:

Other conditions that cause high GGT blood levels are:

  • Alcohol use disorder.
  • Pancreatitis or pancreatic cancer.
  • Diabetes.
  • Congestive heart failure.

If you have abnormal GGT levels, your doctor may recommend additional tests to determine the cause and assess your liver health. Other liver function tests and imaging tests (Ultrasound and MRI) are recommended for a proper diagnosis. Lifestyle modifications, such as reducing alcohol consumption, maintaining a healthy weight, and following a balanced diet, can be beneficial in managing abnormal GGT levels.

Why would Doctors recommend the GGT Blood Test?

The GGT test assesses liver function and helps to diagnose liver and bile duct disorders. Your doctor may recommend the GGT blood test if you experience: 

  • Signs of Liver Disease: If you have symptoms of liver disease, such as jaundice (yellowing of the skin and eyes), unexplained fatigue, abdominal pain, dark urine, or persistent nausea, your doctor may order a liver function panel, which includes the GGT test.
  • Abnormal Liver Enzymes: If you have other liver function tests, such as elevated levels of ALT or AST, your doctor may order a GGT test to get a more comprehensive view of your liver health.
  • Suspected Bile Duct Disorders: GGT levels are elevated in bile duct disorders, such as cholangitis or bile duct block. Symptoms may include pain in the upper right abdomen, fever, and jaundice.
  • Monitoring Liver Disease or Treatment: If you have a known liver disease or are undergoing treatment for liver-related issues, the Gamma GT test may be used to monitor the disease's progression and the treatment's effectiveness.
  • Assessing Alcohol Consumption: If you have a history of alcohol abuse or your doctor suspects alcohol-related liver damage, they may order a GGT blood test.

Symptoms of High GGT Level

Symptoms of abnormal GGT levels include:

  • Decreased Appetite
  • Fatigue
  • Weakness
  • Nausea or vomiting
  • Lack of energy
  • Abdominal pain
  • Jaundice
  • Itchy skin
  • Dark urine
  • weight loss
  • Easy bruising or bleeding

Factors affecting the GGT blood levels

Here are some factors that affect the GGT level in blood.

  • Alcohol
  • Excess intake of magnesium
  • Obesity
  • Tobacco
  • Drugs
  • Antacids

Other Tests to Diagnose Liver Functioning

In addition to a GGT blood test, your doctor may recommend you some other test to check the liver functioning. These blood tests include:

GGT Test price @ Redcliffe Labs

The GGT test price with Redcliffe Labs is Just Rs. 260. If you are looking for a GGT test near me, choose Redcliffe Labs as your trusted diagnostic partner. We will promise you to provide the best diagnostic services right from your home. We offer 3600+ blood tests at affordable prices. We have made our prices highly competitive and affordable so no one will be left behind to get tested. You can book a test online within a minute. So, what are you waiting for? Book your GGT blood test now!

ggt test price

Other Liver Function-Related Tests/Packages That You Can Book With Redcliffe Labs

Tests/Packages NamePrice in INR
Liver Function Extended Panel₹599
Vital Screening Package₹599
Smart Full Body Checkup₹799
Liver Kidney Function Profile₹999
Smart Full Body Check up with Vitamin D₹1099
Fit India Full Body Checkup with Vitamin Screening₹1499
Anti Soluble Liver Antigen (Anti SLA)₹1400
Liver Kidney Microsomal (LKM) Antibody Test₹1600
Advance Plus Full Body Checkup₹2099
Autoimmune Liver Diseases Profile IgG₹8700
Polycystic Liver Disease Gene Panel₹20000

Check your GGT Level with Redcliffe Labs!

If you are experiencing any symptoms or have concerns about your liver health, alcohol consumption, or any other health issues, it is crucial to consult a healthcare professional. They can evaluate your symptoms, recommend blood tests, and provide appropriate guidance and treatment if needed. Early detection and proper management can lead to better health outcomes. Redcliffe Labs is your trusted provider providing the GGT test at home. You can book a test online, and our expert phlebotomist will collect the blood sample at your doorstep. With our express slots, you will be tested within 45 minutes. So, if you are experiencing the symptoms mentioned, it's time to book a GGT test.

Conclusion

The gamma-glutamyl transferase (GGT) test helps detect the likelihood of liver damage, bone disorder, bile duct obstruction, and even alcohol use disorder. The GGT enzyme, mainly present in the cells and tissues of the liver, carries out various liver functions. It is one of the first liver enzymes that spike up when the liver undergoes any damage, inflammation, or liver duct constriction. 

Generally, a GGT test, done with another liver function test, helps determine the specific cause of symptoms- nausea, jaundice, stomach issues, appetite loss, and more. Consult your doctor to know more about the GGT test and get evaluated for any condition.

FAQ’s

1. What is the GGT test?

The GGT (Gamma-Glutamyl Transferase) test measures the GGT enzyme level in the blood. It assesses liver and bile duct health, detects liver diseases, and identifies alcohol consumption or medication effects.

2. Is there any risk of the GGT Test?

No, there is no risk of a GGT blood test. The expert phlebotomist will draw the blood from standard procedure. However, there is no risk of infection or any other diseases. 

3. What does the high blood GGT level mean?

The high level of GGT means the disease is damaging your liver.  However, the elevated GGT level causes Hepatitis, Cirrhosis, Cholestasis, and liver tumor.  

4. What is the GGT Test price?

The GGT test price is INR 260 at Redcliffe Labs. You can book an online appointment with us; all our packages are highly affordable.

5. What level of GGT is dangerous?

The dangerous level of GGT is 275-550 U/L in men, 190-380 U/L in women. If your GGT level is high, you require medical help and proper treatment.

6. Does high GGT mean cancer?

The GGT test does not indicate the cause of liver damage or cancer. However, high GGT causes severe liver disease and may cause liver cancer, hepatitis, and cirrhosis. 

7. What is a high GGT level?

The high level of GGT may vary depending on various factors, including age and sex. 

The normal range lies between 5 to 40 U/L. Above this range, the GGL level will be considered as high.

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1 Comments

  • stephanie Vd Merwe

    Sep 3, 2024 at 3:52 PM.

    I am so worried, my GGT levil is 519!! What do I do, more tests, please help?? +

    • MyHealth Team

      Sep 5, 2024 at 8:29 AM.

      A GGT level of 519 is significantly elevated and may indicate liver issues. Consult your doctor for further evaluation and additional tests, such as liver function tests or imaging studies. Review any medications you’re taking, and make lifestyle changes like avoiding alcohol and eating a balanced diet. Prompt medical attention is important for accurate diagnosis and treatment.

    • MyHealth Team

      Sep 5, 2024 at 6:48 AM.

      A GGT level of 519 is significantly elevated and may indicate liver issues. Consult your doctor for further evaluation and additional tests, such as liver function tests or imaging studies. Review any medications you’re taking, and make lifestyle changes like avoiding alcohol and eating a balanced diet. Prompt medical attention is important for accurate diagnosis and treatment.

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