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Vitamin B12 Test Guide: High, Low, and Normal Levels

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Vitamin B12 Test Guide: High, Low, and Normal Levels

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Medically Reviewed By
Dr Divya Rohra

Written By Dr. Ragiinii Sharma
on Mar 28, 2022

Last Edit Made By Dr. Ragiinii Sharma
on Jul 4, 2024

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Vitamin B12 Test
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Vitamin B12 is crucial for different physiological functions related to brain health, nerve functions, and optimal blood cell production in the body. However, the deficiency can lead to numerous complications, which is where the routine Vitamin B12 test comes into play.

It is a routine blood test that analyzes Vitamin B12 in the bloodstream. The test can be alternatively done as a urine test, but blood tests are prevalent and provide more accurate results.

This article will explore more about the significance of the Vitamin B12 test, the normal and abnormal levels, and the treatment options associated with such complications.

What is the significance of doing a Vitamin B12 Test?

The Vitamin B12 test monitors the Vitamin B12 levels in the body. Since both high and low levels can impose severe complications, regulating the Vitamin B12 levels is crucial for the body's healthy functioning.

A doctor might prescribe a Vitamin B12 test for:

1. Possible Vitamin B12 deficiency

Vitamin B12 deficiency is common in several countries like India, central and north America, Mexica, and parts of Africa. More or less, the occurrence of Vitamin B12 deficiency is an alarming concern worldwide.

So, if you present with typical symptoms of Vitamin B12 deficiency like lacking balance, nausea, confusion, fast heartbeat, memory loss, sore mouth, etc., your doctor might prescribe the Vitamin B12 test to clarify their suspects.

2. Pernicious Anemia diagnosis

Since vitamin B12 is associated with the production of blood cells in the body, lack of this vitamin can lead to pernicious anemia. The condition is common in patients who lack intrinsic factors in their stomachs.

Lack of intrinsic factors in the stomach is the primary contributing factor. Common symptoms for this condition include fatigue, loss of appetite, weakness, and unexplained weight loss.

3. Elevated Folate Levels

Patients complaining about neurological issues often have underlying and undiagnosed Vitamin B12 deficiency. Excess folic acid levels in the bloodstream masks the symptoms of Vitamin B12 deficiency; hence getting a Vitamin B12 test can help ascertain the complications.

When will Your Doctor Prescribe a Vitamin B12 Test?

Besides the conditions mentioned above, your doctor will prescribe a Vitamin B12 test if you present with one or multiple of the following symptoms:

  • Confusion
  • Weakness
  • Loss of appetite
  • Tachycardia
  • Tingling sensation in the body’s extremities
  • Balance-related issues
  • Bleeding gums
  • Diarrhea
  • Constipation
  • Pale skin

Depending on the symptoms, the patients will be prescribed all the associated diagnostic tests to rule out any disease that the doctor suspects.

Also, since Vitamin B12 is commonly found in animal food sources like meat, milk, eggs, cheese, etc., vegetarians and vegans need to get regular Vitamin B12 tests done to ensure they aren’t deficient.

Vitamin B12 Test Results – What is the b12 Normal, Low, and High Range?

The vitamin b12 normal range in the body is 200 to 600 pg/mL. This is the standard reference level for blood tests.

If you are getting a urine examination done, the normal range is under 3.8 mcg/mC.

High Vitamin B12 levels

Vitamin B12 levels above 800 pg/mL are considered high. This is a sign of concern and can indicate complications like liver disease, renal dysfunction, or leukemia.

Naturally, high vitamin B12 often indicates signs of underlying dysfunction or disease in the body. So, the doctor can opt for further testing to rule out severe complications before further treatment.

Low Vitamin B12 levels

Vitamin B12 levels below 150 pg/mL are considered low. This can indicate underactive thyroid functions, pernicious anemia, or prevalent neurological symptoms.

Low levels require supplementation or injections to absorb the needed vitamins and minerals in the body efficiently. Therefore, individuals should only take the prescribed dosage of the supplements or injections.

How is the Vitamin B12 Test Done?

As mentioned before, a Vitamin B12 test can be done via two methods – a blood test or a urine test.

The blood test is a more standard and common testing method and is often done on an empty stomach for precise results. Therefore, you will be advised not to eat or drink anything 6-8 hours before the test.

Depending on your symptoms, your doctor might prescribe tests to check methylmalonic acid levels (MMA). These additional tests indicate the preliminary signs of Vitamin B12 deficiency in the patients.

What are the Side Effects of Vitamin B12 Test?

Vitamin B12 test is a routine blood test that doesn’t impose any severe risks or side effects. The maximum risk that one can experience is the pricking sensation when the lab assistant takes the blood sample.

In very rare cases, a patient might experience risks of hematoma or infection at the site from where the blood was drawn.

What is the Cost of Vitamin B12 Test in India?

The cost of the Vitamin B12 test in India typically starts from INR 1200. But, the rates can vary depending on the city and the laboratory the patient is getting the tests from.

Conclusion

Vitamin B12 plays a vital role in our body, so abnormal levels of this micronutrient can be alarming. However, testing and timely diagnosis and treatment can overcome the complications and allow the individuals to live a comfortable life. People on a strict plant-based diet should get routine Vitamin B12 tests to rule out possibilities of deficiencies in the body.

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10 Comments

  • Lakshmi Devi

    Sep 8, 2024 at 6:33 AM.

    My age48 my b12 test report 160

    • MyHealth Team

      Sep 11, 2024 at 4:13 PM.

      A B12 level of 160 pg/mL is low and could indicate a deficiency. B12 deficiency can lead to fatigue, weakness, and other health issues. It's important to address this with your healthcare provider, who may recommend B12 supplements or dietary changes to help increase your levels.

  • Deann

    Jun 13, 2024 at 3:42 PM.

    My B12 is high at 1849 on 04/10/24 in 06/28/23 it was only 359. My doctor told me not to worry about it. Why would this be.?? My A1c is 5.7 and again I was told not to worry about it. But I've read online that having high B12 could be a problem well different problems. My doctor always tells me I'm fine; my bloodwork is great. But is it great.?? Thank-you

    • MyHealth Team

      Jul 5, 2024 at 9:55 AM.

      Hello! A vitamin B12 level of 787 is typically within the normal range. So you don't need to get worried.

    • Lily

      Jul 3, 2024 at 4:23 PM.

      My vitamin B12 is 787 and I don't know if it's in the normal range or high. Is there any concerns?

    • MyHealth Team

      Jun 14, 2024 at 12:31 PM.

      Your B12 level of 1849 pg/mL is high compared to 359 pg/mL previously. This could be due to supplements, diet, or lab variations. Your doctor isn't worried, likely because your other tests are normal. An A1c of 5.7% indicates prediabetes, but your overall health seems good. Consult your doctor for personalized advice.

  • Happytalk

    Apr 26, 2024 at 11:43 PM.

    Hi, I recently had a FBC carried out which all came back normal. My B12 levels were double what they should be however my Doctor (I use an online system) has said no further action. Needed! I have had an ongoing issues with digestion/malabsorption for 3.5yrs...and I've read high b12 could be due to problems with the Liver. I'm wondering why she would dismiss the b12 result? I have a telephone appointment booked with her in a couple of weeks...as I'm concerned! Thank you for your time :)

    • Myhealth Team

      May 20, 2024 at 12:48 PM.

      It's natural to feel concerned about your elevated B12 levels, especially given your ongoing digestive issues. While high B12 levels can sometimes indicate liver problems, there could be other explanations. Your doctor may have chosen not to take immediate action based on additional factors or may plan to discuss further during your upcoming appointment. It's essential to communicate your concerns during the appointment for clarification and guidance.

  • Linda Murrell

    Apr 20, 2024 at 6:00 PM.

    My blood work lab results were all in the normal range....WBC, RBC, Platelets, Ferratin, but my Vitamin B 12 was 1673. Is there cause for concern?

    • Myhealth Team

      Apr 23, 2024 at 6:53 AM.

      Elevated Vitamin B12 levels, like 1673 pg/mL, may warrant further investigation. Consult a doctor further to determine the cause.

  • Ilene allen

    Mar 29, 2024 at 9:25 AM.

    I found out that my B 12 is deficient and is low. I have been gaining weight unnecissarily. Is that the reason?

    • Myhealth Team

      Apr 5, 2024 at 7:36 AM.

      Hi, Vitamin B12 deficiency can contribute to weight gain due to reduced energy levels and metabolism, but other factors may also be involved. It's essential to consult a healthcare professional for personalized advice and management. Thankyou

  • Sandor Lipcsik

    Feb 8, 2024 at 2:07 AM.

    B12level is 1655 pg/mL and I’m on 300mg of Phenytoin. Is B2 high?

    • Myhealth Team

      Feb 8, 2024 at 6:15 AM.

      Hi Sandor, Your B12 level is 1655 pg/mL, which is higher than the normal range. However, you're currently taking 300mg of Phenytoin. Phenytoin intake can sometimes interfere with B12 absorption, leading to elevated B12 levels. In this situation, it's advisable to consult your doctor. They can provide appropriate guidance based on your overall health and treatment plan. Thankyou

  • Karla Malone

    Feb 1, 2024 at 8:34 PM.

    I have high levels of B12 2000 to be exact what does that mean

    • Myhealth Team

      Feb 3, 2024 at 3:18 PM.

      Hi Karla, High B12 levels could be due to supplements, liver/kidney issues, blood disorders, or certain medications. Consult with a healthcare professional to identify the cause and determine the appropriate steps. Thankyou

  • Carmen s Leone

    Jan 3, 2024 at 12:40 AM.

    My lab results shows my Vitamin 12 is above normal. I taken Mult Vitamin Vitality 500% 10%, I am on tube feeding Boost 530.

    • Myhealth Team

      Jan 4, 2024 at 12:04 PM.

      If your vitamin B12 is above normal and you're taking a multivitamin and Boost 530, consult your healthcare provider to assess if any adjustments are needed for your specific health situation.

  • glenda varner

    Nov 17, 2023 at 6:54 PM.

    my b12 is high what do I do to get down

    • Myhealth Team

      Nov 20, 2023 at 12:40 PM.

      High B12 levels: Consult a healthcare professional for personalized advice and possible adjustments to diet or supplements.

  • propecia-Ked

    Dec 27, 2022 at 12:45 PM.

    I’m not sure where you’re getting your info, but good topic. I needs to spend some time learning much more or understanding more. Thanks for wonderful info I was looking for this information for my mission.

    • Myhealth Team

      Dec 28, 2022 at 8:46 AM.

      Thanks for the appreciation. For more health queries visit https://redcliffelabs.com/health-community/ and you would receive an appropriate response and along with that you would also receive more content on Health management on this platform

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