What Diseases Are Caused by Vitamin B5 Deficiency?

Medically Reviewed By
Dr. Geetanjali Gupta
Written By Anjali Dubey
on May 29, 2026
Last Edit Made By Anjali Dubey
on May 29, 2026

Everything you eat gives your body energy, but Vitamin B5 is what helps turn that food into fuel. It helps your body change macronutrients into ATP, which powers your heart, brain, and muscles. Even though B5 is found in almost all foods, certain lifestyles and health conditions can still leave you low. If you do not get enough Vitamin B5, you might feel tired, but it can also cause skin problems, digestive issues, and nerve damage. In this article, we will look at what happens in your body when Vitamin B5 is missing.
This blog explains the deficiency of this vitamin in your body and the health conditions that can result from it. You will also learn how to make sure you get enough B5, even with a busy lifestyle.
Also Read: Role of Vitamins and Nutrients in Managing Weight Naturally
What Exactly is Vitamin B5 (Pantothenic Acid)?
Vitamin B5 is a water-soluble nutrient that belongs to the B-complex family. Its name, Pantothenic, or Vitamin B5, is a water-soluble nutrient in the B-complex family. Its name, "Pantothenic," comes from the Greek word pantos, meaning everywhere, because B5 is found in almost all plant and animal foods. Its main job is to help make Coenzyme A (CoA), which is needed to break down fats and convert food into energy. Without enough B5, your body cannot work as it should in a balanced diet. Most documented cases have occurred in clinical research settings or in populations suffering from severe malnutrition or famine. However, sub-clinical deficiencies, where you have enough to survive but not enough to thrive, are becoming more common due to the high consumption of highly processed, nutrient-stripped foods.
The top diseases caused by vitamin B5 deficiency
Here are some diseases that can be caused by not getting enough of this important vitamin:
1. Burning Feet Syndrome (Grierson-Gopalan Syndrome)
Burning Feet Syndrome is linked to a severe lack of Vitamin B5. People with this condition often feel burning, heat, tingling, or “pins and needles” in their feet, especially at night. Vitamin B5 is important for keeping nerves healthy and making sure the brain and body communicate well. Without enough B5, nerves can weaken and send pain signals the wrong way. Some people also feel numbness or weakness in their hands and feet. Sometimes, the feet may look red or feel unusually hot or cold. These symptoms can make it hard to sleep, walk, or perform daily activities if left untreated.
2. Adrenal Exhaustion and Hormonal Imbalance
Vitamin B5 helps the body manage stress and maintain hormonal balance. It supports the adrenal glands, which make stress hormones. When B5 is low, people may feel tired all the time, mentally and physically worn out, and emotionally stressed. Some feel tired even after a good rest. Low B5 can also affect mood and hormones, causing irritability, mood swings, low energy, irregular periods, or trouble focusing. Because B5 helps control blood sugar, not having enough can lead to dizziness, shakiness, sudden hunger, and brain fog. Over time, these symptoms can make daily life feel harder and more tiring.
3. Skin and Hair Problems
Vitamin B5 is important for healthy skin and hair growth. Without enough B5, skin can become dry, rough, itchy, or irritated. Some people get acne, rashes, or wounds that heal slowly. This is because B5 helps keep the skin's protective barrier and oil balance. Hair can also suffer, becoming weak, thin, brittle, dull, or breaking easily. Some people may notice their hair turning gray early. These symptoms often develop slowly, so many people do not realize that low B5 might be the cause.
4. Gastrointestinal Problems
Vitamin B5 helps the digestive system work smoothly by supporting energy production and healthy gut function. When the body lacks sufficient B5, digestion may slow down, leading to symptoms such as stomach pain, bloating, nausea, gas, or discomfort after eating. Some people may also lose their appetite because the body struggles to convert food into energy properly. This can lead to weakness, weight loss, and tiredness. Vitamin B5 deficiency may also affect the intestinal lining, making it harder for the body to absorb essential nutrients such as iron, calcium, and vitamins. Over time, poor digestion and nutrient absorption can make a person feel unhealthy, weak, and low on energy almost every day.
5. Neurological and Psychological Problems
Vitamin B5 is important for brain health, nerve function, and making energy. Without enough B5, both mental and physical health can suffer. People may feel anxious, irritated, down, mentally tired, or stressed for no clear reason. Sleep problems like insomnia or restless nights are also common because B5 helps control sleep hormones. Some people have trouble focusing, remembering things, or getting brain fog. In serious cases, muscle coordination can weaken, making tasks like writing, walking, or buttoning clothes harder. Since the brain needs a lot of energy, low B5 can leave someone feeling physically and emotionally worn out.
Who is at Risk?
Although Vitamin B5 deficiency is rare, some groups need to pay extra attention to their intake:
- Alcohol interferes with the absorption of all B vitamins and increases their excretion from the body.
- People with Malabsorption Syndromes: Those with Celiac disease or Crohn's may struggle to absorb B5 effectively.
- People under constant stress: High stress uses up B5 faster because the body needs more to make stress hormones like cortisol.
- People who eat a lot of processed foods: Processing grains and canning vegetables can remove up to 75% of their natural B5.
How to Prevent Vitamin B5 Deficiency: Best Vegetarian Food Sources
Here are some foods that can help prevent Vitamin B5 deficiency:
Shiitake Mushrooms
Shiitake mushrooms are a top vegetarian source of Vitamin B5. They support energy, nerve health, and immunity. Adding them to soups, stir-fries, or salads can boost your daily B5 intake and help your overall health.
Avocados
Avocados have healthy fats and plenty of Vitamin B5. They support skin health, brain function, and energy. Eating avocados often in salads, sandwiches, or smoothies can help prevent Vitamin B5 deficiency.
Sunflower Seeds
Sunflower seeds are a healthy snack full of Vitamin B5 and other nutrients. They help keep nerves healthy, boost energy, and support skin. You can eat them roasted or add them to smoothies, oats, or salads.
Sweet Potatoes
Sweet potatoes are healthy vegetables with Vitamin B5, fiber, and antioxidants. They help with digestion, energy, and immunity. Eating boiled, roasted, or baked sweet potatoes can help you get better nutrition.
Broccoli
Broccoli is a green vegetable with Vitamin B5 and many other nutrients. It helps your immune system, skin, and digestion. Eating steamed or cooked broccoli often can help keep your vitamin levels healthy.
Also Read: Vitamins Tests: Types, Names & Benefits
Final Thoughts: Prioritizing Your Path to Wellness
Vitamin B5 might not be called a superfood, but it is essential for your metabolism and nervous system. It helps with problems like Burning Feet Syndrome and keeps your stress hormones balanced. Remember, you do not have to manage your nutrition by yourself.
To make sure your Vitamin B5 levels are good, Redcliffe Labs offers a simple solution. Their free home sample collection lets you avoid waiting at clinics and check your health from home. Their digital reports explain your results in clear language, so you can make better choices for your health. Do not wait until you feel tired; use professional tools to keep your Vitamin B5 at the right level and working for you.
FAQs
What happens if vitamin B5 is low?
Low vitamin B5 levels can make you feel tired, weak, irritable, and mentally exhausted. Some people may also experience headaches, numbness in the hands or feet, poor sleep, or stomach discomfort. Since vitamin B5 helps the body produce energy, a deficiency can affect daily functioning and overall health if ignored for a long time.
What is the richest source of vitamin B5?
Organ meats, such as liver, are considered among the richest sources of vitamin B5. Apart from that, foods like chicken, eggs, mushrooms, sunflower seeds, avocados, and whole grains also contain good amounts. Eating a balanced diet with fresh and natural foods usually provides enough vitamin B5 for the body’s daily needs.
Where can I get vitamin B5 naturally?
You can get vitamin B5 naturally from many everyday foods. Good sources include eggs, milk, chicken, fish, mushrooms, broccoli, sweet potatoes, avocados, peanuts, and whole grains. Since vitamin B5 is found in both plant and animal foods, most people can easily meet their needs through a healthy, balanced diet.
What are the negative effects of vitamin B5?
Insufficient vitamin B5 intake may cause fatigue, weakness, mood changes, headaches, and digestive problems. In rare cases, people may feel tingling or burning sensations in their feet. Excess intake from supplements can sometimes lead to diarrhea or stomach upset. Maintaining the right balance is important for healthy energy production and body function.
Does vitamin B5 lower cholesterol?
Vitamin B5 itself does not directly lower cholesterol, but a form called pantethine may help improve cholesterol levels in some people. Research suggests it may reduce bad cholesterol and support heart health when combined with a healthy lifestyle. However, it should not replace medical treatment or a doctor’s advice for cholesterol management.
How to treat B5 deficiency?
Vitamin B5 deficiency is usually treated by improving the diet and eating more nutrient-rich foods. Doctors may also recommend vitamin B5 supplements if the deficiency is severe. Including eggs, fish, meat, dairy products, whole grains, and vegetables in daily meals can help restore healthy vitamin levels and improve symptoms over time.
What fruits contain vitamin B5?
Several fruits contain small amounts of vitamin B5. Avocados are one of the best fruit sources. Other fruits, such as bananas, oranges, grapefruit, strawberries, and watermelon, also provide some vitamin B5. Although fruits alone may not meet the full daily requirement, they can still support overall nutrition as part of a balanced diet.
Can a poor diet lead to vitamin B5 deficiency?
Yes, a poor diet can increase the risk of vitamin B5 deficiency, especially if meals lack fresh vegetables. fruits, whole grains, dairy, or protein-rich foods. People who eat highly processed foods regularly may not get enough essential nutrients. Long-term unhealthy eating habits can slowly affect the body’s energy and overall health.
What happens if vitamin B5 deficiency is left untreated?
If vitamin B5 deficiency is not treated, symptoms may gradually worsen. A person may experience ongoing fatigue, weakness, mood changes, sleep problems, digestive discomfort, and nerve-related symptoms such as tingling or burning in the feet. An untreated deficiency can affect daily life, work performance, and long-term physical and mental well-being.
What is the difference between vitamin B5 deficiency and other B vitamin deficiencies?
Vitamin B5 deficiency mainly affects energy production and may cause tiredness, burning feet, irritability, and weakness. Other B vitamin deficiencies have different symptoms. For example, vitamin B12 deficiency can cause anemia and nerve damage, while vitamin B1 deficiency affects the heart and nervous system. Each B vitamin supports different functions in the body.


