Test Details

U1RNP Antibodies, SS-A / Ro Antibody, SS-B / La Antibody, SCL-70 (Scleroderma) Antibody, J...Read more
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INCLUDES7 Parameters
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REPORTS (T&C)5 days
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SAMPLE TYPE

Blood

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FASTINGNot Required

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Includes

7 Test Parameters

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Extractable Nuclear Antigen (ENA) Panel, Quantitative

7 PARAMETERS INCLUDED

A quantitative version of the ENA panel that measures antibody levels against specific autoantigens to help diagnose autoimmune disorders.

7 PARAMETERS INCLUDED

  • Centromeres
  • JO-1
  • Scl-70
  • Smith (Sm)
  • SS-A (RO)
  • SS-B (La)
  • U1RNP

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Parameters 94

10

Heart

1093

Diabetes (Hba1c)

18

Liver

17

Kidney

6

Diabetes / Sugar

1086

Infection

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1093

Diabetes (Hba1c)

1085

Lipid

18

Liver

17

Kidney

1086

Infection

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Fit India Full Body Checkup with Free HbA1c
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18

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17

Kidney

1086

Infection

22

Thyroid

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Parameters 96

10

Heart

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1085

Lipid

18

Liver

17

Kidney

1086

Infection

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154503399
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10

Heart

23

Vitamins

18

Liver

17

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5

Bone / Joints

6

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Verified by Medical Expert

Dr. Himani Pandey

Verified By

Dr. Himani Pandey

verified
Anjali Dubey

Written By

Anjali Dubey

Table of Content

Introduction of ENA Profile Test 

Antibodies protect the body by eliminating and binding unwanted substances. The immune system produces antibodies. Extractable Nuclear Antigens (ENAs) are proteins found in the nucleus of cells that can be extracted from the body. To diagnose, doctors may recommend an ENA profile test. You may wonder, ‘What is the ENA profile test?’ An ENA profile test helps diagnose the presence of autoantibodies. Autoantibodies are the antibodies that mistakenly attack your body’s tissues. 

Muscle pain, hair loss, fever, and fatigue can indicate an autoimmune disorder. If you see these signs, take the ENA profile test from Redcliffe Labs. Redcliffe Labs, an omnichannel purpose-driven diagnostic service provider, offers 3600+ tests at an affordable price, a home sample collection, and the shortest turnaround time (TAT). You can book the ENA profile test from our website and mobile app (available at both the Play Store and the App Store). 

Test details in Brief 

Also known as  Antibodies to saline-extracted antigens, Anti-RNP, Anti-Ribonucleoprotein Anti-U(1)RNP, Anti-SmRNP, Anti-SSA, Anti-Sjogren Syndrome A, Anti-SSB, Anti-Sjogren Syndrome B, Anti-Sm
Purpose  To detect autoantibodies that react with protein in the cell nucleus 
Preparation  Don’t take any unprescribed over-the-counter medicine before the test. 
Fasting  The test needs no fasting. 
Get Reports Within  5 Days 
Cost  INR 7600 

What is the ENA Profile Test? 

The Extractable nuclear antigen or ENA profile test is a blood test that looks for antibodies to 7 proteins in the body. The ENA profile test list includes the following: 

  • Anti-centromere is associated with systemic sclerosis, primary biliary cholangitis, and Sjogren’s syndrome. 
  • Anti-JO-1- JO-1 is an antibody linked to various autoimmune diseases, mainly myositis. This antibody targets histidyl-tRNA synthetase, an enzyme involved in protein synthesis. 
  • Ant-Sci-70- It is found in lupus and Scleroderma autoimmune disorders.
  • Anti-Sm (anti-smith antibody) is found in lupus and MCTD autoimmune disorders. 
  • Anti-SSA (anti-Ro) is a ribonucleoprotein antigen found in various autoimmune disorders. It is usually linked to systemic lupus erythematosus and Sjogren’s syndrome. 
  • Anti-SSB (anti-La) is common in certain autoimmune disorders, such as lupus and Sjogren’s syndrome. It is also present in neonatal lupus, autoimmune hepatitis, and polymyositis. 
  • Anti-U1RNP (anti-ribonucleoprotein) is associated with MCTD, SLE, SSc, pulmonary damage, and myositis. 

These types of antibodies are autoantibodies. The immune system produces autoantibodies that target something made of the body’s tissue. The ENA profile test helps detect and diagnose the presence of these antibodies, which helps prevent severe health complications. The ENA profile test price is INR 7600 at Redcliffe Labs.

Is the ENA and ANA test the Same? 

No, the ANA and ENA tests are not the same. An ANA test is a screening test for autoimmune disorders that identifies and counts the amount of antinuclear antibodies in the body. An ENA test is more specific than an ANA, specifically identifying proteins working against antibodies. 

A healthcare provider may suggest the ANA test to diagnose autoimmune diseases and recommend the ENA test as a follow-up after a positive ANA test. 

What is the Purpose of the ENA Profile Test? 

The extractable nuclear antigen (ENA) profile test is vital for diagnosing and managing autoimmune disorders. Here is a detailed description of its purpose. 

  • Diagnose Autoimmune Disorder—Autoantibodies are antibodies in the body that attack cells, tissues, and organs, leading to autoimmune disease (disorder). Early (timely) diagnosis of these antibodies can help manage and treat autoimmune disorders. 
  • Identify Specific Antibodies—The test analyzes antibodies that work against a group of proteins, including Ro, La, Sm, Sci-70, Jo1, and RNP. The identification of these antibodies indicates the presence of an autoimmune condition. 
  • Monitoring the Progression of Disease—The ENA profile test can monitor the activity or progression of disease and the response to treatment in a person diagnosed with an autoimmune condition. It can help effectively manage, treat, and align therapeutic strategies. 
  • Understand the Response of Autoimmune Disease- The ENA blood test identifies the nature of a person’s autoimmune response by detecting specific autoantibodies. This helps prepare a personalized and strategic plan for improving and managing the disease. 
  • Clinical Understanding- The ENA profile test results, symptoms, causes, and medical history are interpreted. This approach helps in accurate diagnosis, management, and care. 

What Does the ENA Profile Test Detect? 

The ENA profile test detects: 

  • The ENA profile test detects the presence of autoantibodies in the blood. These autoantibodies can attack or damage tissues and cells, leading to autoimmune disorders. 
  • The test diagnoses autoimmune diseases like Sjogren’s syndrome, scleroderma, and mixed connective tissue disease (MCTD). 
  • The test monitors the progression of autoimmune disease. 
  • The test detects the cause of symptoms like chronic fatigue, swelling, fever, and hair loss. 

What Does the ENA Profile Test Measure? 

A healthcare professional may recommend the ENA profile test after the ANA test. Usually, it measures the level of specific ENA and ANA antibodies in the blood. The ENA profile blood test diagnoses autoimmune disorders, and early diagnosis prevents further serious health complications. 

The ENA Profile test measures the autoantibodies in the body. These autoantibodies affect the body’s tissue, organs, and cells, leading to damage and inflammation. Autoantibodies include:

  • Mixed connective tissue disease (MCTD)
  • Lupus (SLE) 
  • Sjögren's syndrome 
  • Scleroderma 
  • Polymyositis / Dermatomyositis 
  • Systemic Lupus Erythematosus (SLE) 
  • Sjogren's Syndrome

Benefits of Booking the ENA Profile Test from Redcliffe Labs. 

Redcliffe Labs is the leading diagnostic chain in India. We offer comprehensive testing, including routine and genetic testing, at a reasonable price. We offer the ENA profile test price at INR 7600. Here is why you should book the ENA profile test from Redcliffe Labs. 

  • Our test prices (including the ENA profile test price) are affordable, reasonable, and accessible. 
  • We offer a home sample collection service, making diagnostics convenient and accessible for everyone. 
  • We work on our four pillars—accessibility, affordability, accuracy, and awareness—to ensure that India has the right to quality diagnostics. 
  • All our labs follow the highest quality standards per NABL and ISO guidelines. 
  • Consumers receive value benefits worth INR 999/—with every test, including personalized diet plans, health progress reports, and report consultation. 

Steps to Book the ENA Profile Test From Redcliffe Labs

You can book the test from our website or mobile app or search ‘ENA Profile test from Redcliffe Labs.’ Our mobile app is available on both the Play Store and the App Store. 

  • Visit the website, www.redcliffelabs.com 
  • Search for the ENA profile test. 
  • Click on ‘Book Now.’
  • Fill out the required details (address and time). 
  • A phlebotomist will visit your home for a sample collection. 
  • Receive the test reports within no time. 

Follow the same procedure when downloading from the mobile application. You can also visit our collection centers by browsing ‘Redcliffe Labs near me.’ Visit the nearest collection center and get tested. 

Preparation For The ENA Profile Test

The ENA Profile test is a blood test that does not require fasting. However, a healthcare provider may recommend fasting based on your health status. 

Additionally, there are some things you must keep in mind before taking the ENA profile test. 

  • Do not take any over-the-counter medications before the test, and inform your healthcare provider if you are taking any medicines. 
  • Drink 8-10 glasses of water daily to prevent dizziness or lightheadedness before or during the test. 
  • Clear all your queries and doubts with the healthcare provider to clear your mind. 
  • Sleep for 7-8 hours at night. 

The Procedure of the ENA Profile Test

After you book the test from Redcliffe Labs, a certified phlebotomist will visit your home to collect your sample at your selected (preferred) time slot. They follow a seamless collection procedure. 

The ENA profile test procedure is the same as every other blood test. Here is the procedure that the phlebotomist will follow. 

  1. Tie a band around the upper arm to locate an appropriate vein to collect blood.
  2. Once located, they will clean the site with an alcoholic substance to prevent infection. 
  3. They will insert a sterile syringe to draw blood samples. 
  4. Transfer the collected blood sample to a test tube for analysis. 
  5. They will put a cotton swab on the punctured site to prevent bleeding. 
  6. They will ask you to hold it for a couple of minutes. 
  7. Please label the test tube with your details: name, time, and date of sample collection, as well as your address. 
  8. They will transfer the test tube for analysis. 
  9. Once done, you will receive the ENA profile test reports within 5 days. 

Risks Associated With the ENA Profile Test 

Inserting a sterile syringe may possess a minimal risk, which disappears within a timeframe. You may experience: 

  • Infection 
  • Excessive bleeding 
  • Bruising 
  • Lightheadedness or dizziness 
  • Slight pain 

What Do The ENA Profile Test Reports Indicate? 

The ENA Protein test reports may indicate either a low or a high value. Low values result in mild or no autoimmune disorder, while a high value indicates the presence of autoimmune disease or disorders. In both cases, a healthcare professional may recommend additional tests. 

The normal range depends on the ENA profile list being tested. Moreover, the ENA test result may vary depending on lab quality and testing equipment. To prevent complications in test results, book the test from Redcliffe Labs. 

Range  Category 
29 AU/mL or less Negative
30-40 AU/mL  Equivocal 
41 AU/mL or greater  Positive 

What If the ENA Profile Test Reports are Positive? 

Here is what the positive ENA test report means: 

  • It indicates the presence of autoantibodies in your blood. 
  • It means you have an autoimmune disorder. 
  • A healthcare professional may recommend additional testing to diagnose the condition.
  • To confirm the positive report, a doctor observes symptoms like fever, fatigue, muscle pain, and skin rash. 
Autoantibody  Result 
Anti-Jo-1 
  • Usually seen positive in 30% of those with polymyositis 
  • It may be positive for pulmonary fibrosis 
Anti-Sci-70
  • Positive in 60% of people with scleroderma 
  • Highly specific antibody marker for this disease 
Anti-SSB (anti-La)
  • Positive in 60% of people with Sjogren syndrome 
  • Rarely present without anti-SSA 
  • May be positive with lupus and scleroderma 
Anti-SSA (Anti-Ro) 
  • Positive in 75% of those with Sjogren syndrome 
  • It may also be positive with lupus and scleroderma 
Anti-Sm 
  • Positive in 30% of people with lupus
  • Very specific antibody marker for this disease 
Anti-RNP
  • Positive in 95-100% of people with MCTD 
  • It may be positive in people with lupus and scleroderma 

Who Should Take the ENA Profile Test?

People who experience symptoms (such as fatigue or fever) must take the ENA profile test. After the serum ANA profile test has been confirmed, a doctor may recommend it. 

Pregnant women with a lupus diagnosis should also take the ENA profile test. This helps your healthcare provider to monitor for neonatal lupus. Neonatal lupus is a medical condition where your antibodies pass through the placenta to the fetus, leading to severe complications with the fetus. 

What are the Common Symptoms Related to Autoimmune Disorders? 

An autoimmune disorder occurs when your body mistakenly attacks healthy cells, organs, and tissues. A person with an autoimmune disorder may experience the following symptoms: 

  • Muscle aches 
  • Swelling 
  • Numbness and tingling in the feet and hands 
  • Hair loss 
  • Skin rash 
  • Memory loss 
  • Trouble concentrating/ focusing 
  • Dizziness 
  • Lightheadedness 
  • Low-grade fever 
  • Swollen glands 
  • Joint pain 
  • Weight gain or loss 
  • Shortness of breath 
  • Trouble breathing 
  • Loss of appetite 
  • Abdominal pain 
  • Digestive issues 
  • Protein in the urine 
  • Seizures 
  • Depression 
  • Psychoses 
  • Hemolytic anemia or leukopenia 
  • Sensitivity to ultraviolet light 

ENA Profile Test Price @ Redcliffe Labs! 

Redcliffe Labs offers the ENA profile test price at a 45% discount, making the cost from 14,000 to 7,600. The ENA profile test identifies seven parameters to detect the presence of autoantibodies in the blood. However, the ENA profile test price may differ because of various factors. These include:

  • The demand for the test
  • The quality of the laboratory 
  • Discounts and Promotions 
  • Comprehensive fees (lab fees, sample collection, and any applicable professional fees) 

ENA Profile Test

ENA Profile Test Price in Different Cities

City Name Discounted Price
Delhi ₹7600
Noida ₹7600
Mumbai ₹7600
Bangalore ₹7600
Kolkata ₹7600
Pune ₹7600
Lucknow ₹7600
Ahmedabad ₹7600
Hyderabad ₹7600
Chennai ₹7600
Gurgaon ₹7600
Jaipur ₹7600
Faridabad ₹7600
Indore ₹7600
Patna ₹7600

Note: We also offer ENA Profile Test PAN India. Please call the number 8988988787 to check the availability of our services in your area.

Take Precautions and Get Yourself Tested Today! 

The ENA/ANA Quantitative profile test can help diagnose autoimmune disorders. So, if you experience symptoms like fever, fatigue, and hair loss, it is better to book a preventive health checkup and reduce the risk of serious health complications. And obviously, your health should be your topmost priority. So, book the ENA profile test today from Redcliffe Labs.

Frequently Asked Questions

What is the ENA Profile Test?

The ENA profile test looks for antibodies that attack the body’s tissues. These antibodies are called autoantibodies. The test also detects antibodies associated with autoimmune disorders like lupus.

    What conditions does the ENA Profile Test help diagnose?

    The ENA profile test diagnoses autoimmune disorders such as lupus, mixed connective tissue disease (MCTD), scleroderma, Sjogren's syndrome, polymyositis, and dermatomyositis and monitors their progression.

      How is the ENA Profile Test performed?

      The ENA profile test is a blood test performed by collecting a blood sample from a sterile syringe and later transporting it for analysis. Redcliffe Labs offers the test at an affordable and reasonable price.

        Do I need to prepare for the ENA Profile Test?

        The ENA profile test needs no specific preparations, like fasting. However, a healthcare professional may recommend fasting after monitoring your health status.

          What do the results of the ENA Profile Test mean?

          The result of the ENA profile test can be either positive or negative. A positive result indicates the presence of antibodies, while a negative indicates no or few antibodies in the blood.

            How long does it take to get the results of the ENA Profile Test?

            The result time varies depending on the diagnostic lab. However, Redcliffe Labs offers the results of the ENA profile test in the shortest turnaround time (TAT) of 5 days.

              Are there any risks associated with the ENA Profile Test?

              There is no major risk associated with the ENA profile test. A person may experience bleeding, slight pain, and infection because it's a blood test.

                Is the ENA Profile Test covered by insurance?

                Whether or not the ENA profile test is covered by insurance depends on your insurance plan. You can check with your insurance company to confirm the coverage.

                  What should I do if my ENA Profile Test results are positive?

                  If your ENA profile test reports indicate a positive result, consult a rheumatologist. A rheumatologist is an expert in autoimmune and rheumatic diseases. They can analyze the results, perform a physical examination, and perform other tests to confirm the autoimmune disorders.

                    Can the ENA Profile Test detect all autoimmune diseases?

                    No, the ENA profile test cannot detect all autoimmune diseases. However, it can diagnose certain disorders, such as lupus and scleroderma.

                      Can I book a Ena profile/Anti Nuclear Aantibodies (ANA), Quantitative Profile near me?

                      Absolutely! Booking a Ena profile/Anti Nuclear Aantibodies (ANA), Quantitative Profile with Redcliffe Labs is very easy. We offer home sample collection by trained phlebotomists, allowing you to get tested from the comfort of your home. Our services are designed to be convenient and reliable, ensuring quality healthcare is always accessible to you.

                        Can I book a home collection for a Ena profile/Anti Nuclear Aantibodies (ANA), Quantitative Profile?

                        Yes, Redcliffe Labs provides free home sample collection for Ena profile/Anti Nuclear Aantibodies (ANA), Quantitative Profile. A certified and trained phlebotomist will visit your home as per the suitable time that, ensuring a safe, hygienic, and comfortable experience. Your sample is transferred from home to lab in the temperature controlled bag to ensure the integrity. Your report is delivered within the promised timeframe, letting you monitor your health from the comfort of home.