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Dr. Himani Pandey
B.Sc, M.Sc, Ph.D (Molecular Genetics)
Meet Dr. Himani Pandey
Dr. Himani Pandey is a trained geneticist who has long experience of working in the aspects of human clinical genetics. She has more than 15 years of experience in molecular biology, molecular diagnostics, genomics, and genetic testing using Next Generation Sequencing (NGS) and Sanger. She has more than 16 publications in reputed journal. Dr. Himani is heading the lab for automated library preparation and sequencing of Whole Exome, Whole Genome, using different and platforms MGI and illumina sequencer. She has also done certain cortication's including MGI WES (NGS), HLA Typing (NGS), NIPT Yourgene (NGS), Genetittan Microarray Platform.
Area of Expertise
Molecular diagnosis of genetic disorders-
❖ Beta Thalassemia (HBB)
❖ Noonan syndrome (PTPN11)
❖ Hunter syndrome (IDS)
❖ Ectodermal dysplasia A (EDA)
❖ Cockayne syndrome (CKN2)
Von Hippel Lindau (VHL) syndrome
Fabry disease (GLA)
Klippel-Feil syndrome (4 genes- GDF1, GDF3, GDF6, RIPPLY2)
❖ Hearing loss (connexin 26)
Ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome (MBTPS-2) Glucose-6-phosphate dehydrogenase (G6PD3 common mutations mutations)
❖ HFE gene mutations
❖ CYP11B2 gene mutations (Aldosterone deficiency syndrome)
❖ Saposin B gene mutations
❖Vici Syndrome (EPG5)
❖ Hemochromatosis (HFE -two common)
Spondyloepiphyseal dysplasia with congenital joint dislocations CHST3 related
disorder (SED - Omani)
❖ Trechar Collin (TCOF1)
❖ Muscular dystrophy and congenital myopathy (TTN)
Cystic fibrosis One common mutation (Delta F 508)
Achondroplasia
❖ Frontonasal dysplasia 1,2and 3 (ALX3,ALX4,ALX1)
Affiliation
- Senior Scientist, Valerian Chem Pvt. Ltd., University of Delhi South Campus, New Delhi
- Former Associate Scientist, Sandor Life Sciences Pvt. Ltd., University of Delhi South Campus, New Delhi
- Associated with SGPGIMS (Sanjay Gandhi Postgraduate Institute of Medical Sciences), Lucknow through ICMR-funded research projects
- Research association with Directorate of Coldwater Fisheries Research (ICAR), Bhimtal, Uttarakhand
- Research association with National Bureau of Fish Genetic Resources (ICAR), Lucknow
- Academic association with Kumaun University, Nainital, Uttarakhand
- Participated in conferences and workshops organized by AIIMS Delhi, IGIB, DBT, ICMR, INSA, and ICAR
Recognitions
- Senior Scientist, Valerian Chem Pvt. Ltd., University of Delhi South Campus, New Delhi
- Former Associate Scientist, Sandor Life Sciences Pvt. Ltd., University of Delhi South Campus, New Delhi
- Associated with SGPGIMS (Sanjay Gandhi Postgraduate Institute of Medical Sciences), Lucknow through ICMR-funded research projects
- Research association with Directorate of Coldwater Fisheries Research (ICAR), Bhimtal, Uttarakhand
- Research association with National Bureau of Fish Genetic Resources (ICAR), Lucknow
- Academic association with Kumaun University, Nainital, Uttarakhand
- Participated in conferences and workshops organized by AIIMS Delhi, IGIB, DBT, ICMR, INSA, and ICAR
Research & Publications
Research Experience
- Senior Scientist – Valerian Chem Pvt. Ltd., CIF Biotech Building, University of Delhi South Campus, New Delhi (July 22, 2019 – Present)
- Associate Scientist – Sandor Life Sciences Pvt. Ltd., CIF Biotech Building, University of Delhi South Campus, New Delhi (January 16, 2017 – July 14, 2019)
- Research Associate – “Centre for Molecular Medicine at SGPGIMS” funded by ICMR, Department of Medical Genetics, SGPGIMS, Lucknow (November 23, 2013 – January 15, 2017)
- Senior Research Fellow – “Harmonizing biodiversity conservation and agricultural intensification through integration of plant, animal and fish genetic resources for livelihood security in fragile ecosystems” at National Bureau of Fish Genetic Resources (ICAR), Lucknow (January 7, 2013 – November 22, 2013)
- Junior Research Fellow – “Genome Scale Mining of Schizothorax richardsonii Fish Species for Formulation of Selective Breeding Programme” at Directorate of Coldwater Fisheries Research (ICAR), Bhimtal (July 27, 2009 – March 31, 2012)
- Ph.D. Scholar – “Molecular Genetic Characterization of Some Cold Water Fishes using RAPD and Mitochondrial DNA Markers” (July 27, 2009 – September 18, 2012)
Research Publications
- Aradhana D., Amita M., Himani Pandey., Mandal K (2019). “Yield of molecular testing in VHL and isolated VHL associated tumors in an Indian cohort”. South Asian Journal of Cancer.
- Dhanya Lakshmi N., Himani Pandey, Amita M., Mandal K., Gupta R., Ratna D. P., Shubha R Phadke (2017). “Noonan syndrome in Indian children: The hotspots in PTPN11.” Indian Paediatrics.
- Shivani Mishra, Himani Pandey, Priyanka Srivastava, Kausik Mandal, Shubha R Phadke (2018). “Connexin 26 (GJB2) mutations associated with Non-Syndromic Hearing Loss (NSHL) in Indian Population.” Indian Journal of Paediatrics.
- Srivastava P, Pandey H, Agarwal D, Mandal K, Phadke SR. (2017). “Spondyloepiphyseal Dysplasia Omani type: CHST3 Mutation Spectrum and Phenotypes in Three Indian Families.” American Journal of Medical Genetics A.
- Poonam Singh Gambhir, Himani Pandey, Kausik Mandal, Prabhaker Yadav, Amita Moirangthem, Shubha R Phadke (2020). “Hypohidrotic Ectodermal Dysplasia in Indian boys: reporting two novel variants in the EDA gene.” Journal of Indian Paediatrics.
- Sati J, Sah S, Pandey H, Ali S, Sahoo PK, Pande V and Barat A (2013). “Phylogenetic relationship and molecular identification of five Indian Mahseer species using COI sequence (Bar-codes).” Journal of Environmental Biology.
- Himani Pandey, Barat A., Singh BK. and Ali S. (2013). “Genetic diversity within and between four genus of Coldwater fishes using RAPD markers and implication for conservation.” Journal of Ecophysiology and Occupational Health.
- Himani Pandey, A. Barat, B. K. Singh, Prabhati K. Sahoo, S. Ali, and P. C. Mahanta (2013). “Comparative Phylogenetic Study of four Coldwater fishes based on targeted 16S RNA mitochondrial gene.” Journal of Ecophysiology and Occupational Health.
- Ali S., Barat A., Pandey H., Sivaraman GK., PK Sahoo., and Sati J. (2014). “Mitochondrial DNA variation and population genetic structure of snow trout Schizothorax richardsonii from Himalayan Regions of India.” Journal of Ecophysiology and Occupational Health.