Table of Content

Introduction to Immunoglobulin G (IgG) Test

The immune system releases proteins called antibodies to fight against germs, infections, harmful substances, and antigens entering the body. There are five types of antibodies; each has its specific function: IgA, IgG, IgM, IgE, and IgD. Deficiency of these may lead to autoimmune disease. The IgG test is a blood test that detects the functioning of IgG antibodies in the immune system. Allergies are common during IgG deficiency. If you have any questions, take the IgG test from Redcliffe Labs. 

Redcliffe Labs is a pan-India diagnostic lab offering 3,600+ tests. We offer a home sample collection service, making our services accessible to everyone. The IgG blood test costs INR 390, and the price usually differs from city to city. 

Test Details in Brief 

Immunoglobulins and Its Types

Immunoglobulins (Ig) are antibodies that fight against bacteria, viruses, germs, and infections. Ig is a protein produced by plasma cells, normally found in blood, saliva, breast milk, tears, and the lining of the respiratory tract and digestive system. Deficiency of immunoglobulins increases the risk of infection, while high levels of immunoglobulin show that you have an allergy or an overactive immune system. There are 5 types of immunoglobulin. These are: 

• Immunoglobulin A (IgA) 
• Immunoglobulin G (IgG) 
• Immunoglobulin M (IgM) 
• Immunoglobulin E (IgE)
• Immunoglobulin D (IgD) 

Immunoglobulin A: IgA antibodies protect the mucous membranes of the sinuses, stomach, intestines, and lungs. There are two subclasses of IgA, IgA1 and IgA2. These antibodies account for 15% of total immunoglobulins. 

Immunoglobulin M: IgM antibodies instantly respond to a new infection, providing relief from short-term protection. IgM works before IgG comes into action. 

Immunoglobulin G: Almost 70-80% of the immunoglobulins are IgG in the blood. Your immune system produces these antibodies to fight with initial symptoms. IgG antibodies fight against microorganisms whenever exposed. 

Immunoglobulin D: IgD is generally present in the plasma membranes of B lymphocytes and the blood serum. This antibody helps prevent autoimmune diseases, allergic reactions, and infections. 

Immunoglobulin E: IgE is present in small amounts in the blood. IgE antibodies help fight against allergies, allergic diseases, or parasitic infections. 

What is the Purpose of the IgG Test? 

Your immune system produces antibodies that protect against bacteria, viruses, and allergens. The main purpose of the IgG test is to necessitate the immunoglobulin G levels in the blood. An IgG blood test can also help detect illness, infection, or chronic inflammation. 

What Does The IgG Test Measure?

Although the price of the IgG test differs from lab to lab, its function doesn’t. The test can help measure the reason for excess, deficient, or normal levels of Immunoglobulin G antibodies in the blood. Any abnormality may increase the risks of infections, germs, and harmful substances caused by viruses, bacteria, or fungi. IgG blood tests can also measure the reoccurrence of infections and the reason for chronic infections. 

What is the IgG Test Used For? 

The IgG blood test checks for a deficiency or excess of IgG antibodies in the blood. The test provides immense information about your body’s functioning, health, and immune system. Immunoglobulin G is necessary for your body. It helps in protecting against infections or germs caused by bacteria or viruses. 

The IgG blood test diagnosis can help identify the primary reason for high or low IgG levels in the blood. There are two major reasons for high IgG levels and low IgG levels. High IgG levels can be due to polyclonal or monoclonal, while low IgG levels can be hereditary or acquired. 

What Does The IgG Test Detect?

The IgG test helps detect the IgG deficiency. Also, the test can detect: 

• If a person has an infection 
• Any suspected immunodeficiency in a child
• Normal or unusual infections in a child
• Allergies or any underlying autoimmune condition 
• Diseases such as celiac disease, juvenile idiopathic, or arthritis

Symptoms of IgG Test 

IgG antibodies prevent infections, germs, and diseases from bacteria, viruses, and harmful substances. Excess or low amounts of IgG may lead to severe health issues. Some common symptoms of IgG deficiency are: 

• Recurrent infection
• Infection in the respiratory tract 
• Digestive issues (stomach or intestines) 
• Chronic diarrhea 
• Chronic inflammation 
• Abnormal immunoglobulin production 
• Bronchitis 
• Ear infection 
• Pneumonia 
• Sore throat 
• Severe infection 
• Gastrointestinal infection 
• Sinus infection 
• Respiratory infection 

What May Cause IgG Deficiency? 

A major cause of IgG deficiency is inheritance, genetics, or hereditary. These are rare, but one of the primary reasons. Other causes of IgG deficiency include: 

• Aging 
• Chemotherapy 
• HIV/AIDS infection 
• Protein-losing conditions 
• Hematologic malignancies 
• Solid-organ transplantation (secondary cause of IgG deficiency) 
• Effects of therapeutic drugs 

These causes may lead to IgG deficiency in people, which can cause ear infections, pneumonia, bronchitis, throat infections, sinus infections, and gastrointestinal infections. 

These causes may also cause kidney damage, leukemia, or autoimmune disorders such as agammaglobulinemia, CVID, x-linked agammaglobulinemia, ataxia telangiectasia, Wiskott-Aldrich syndrome, hyper-IgM syndrome, and severe combined immunodeficiency (SCID). 

Why Do You Need The IgG Test? 

The IgG test helps detect any deficiency and diagnose an infection. If you suspect the above symptoms, take the IgG test. Some other factors indicating the need for an IgG test include: 

• Consistent diarrhea
• Unexplained weight loss 
• Fevers 
• Allergies 
• Skin rashes 
• Tiredness after travelling 
• HIV or AIDs 
• Multiple myeloma 
• Severe health condition 

The IgG test can help determine the functioning of the immune system after recovery or vaccination, know the chances of recurrence, and the reason for IgG infection. 

Why A Doctor May Recommend The IgG Test? 

IgG levels are necessary for the body’s overall functioning. Your doctor may recommend the IgG blood test as a part of a routine health checkup. IgG tests can help them evaluate and monitor your overall health, especially linked to excess or low immunoglobulin production. 

A doctor might also recommend an IgG test as a part of other tests to determine immunoglobulin levels. If they detect immune system disorders that may affect your body’s functioning to fight against infection or disease. Extreme fatigue, recurring infection, swelling, and unexplained rashes are other signs your doctor might recommend the IgG test. 

Preparation for the IgG Test 

The IgG test is a simple blood test. There is no need for major preparations, and unless advised otherwise, no fasting is required. Avoid wearing long-sleeved shirts during the IgG blood test. The test can make you feel tired or weak, so make sure you are well-hydrated. 

Alcohol and smoking may hinder test results, so avoid them. Because antibody deficiency may stress you out, practice yoga, meditation, and deep-breathing exercises. These are some basic precautions that can help you maintain normal well-being and provide a correct report. 

IgG Test Procedure 

IgG antibodies are present in the blood; your doctor requires blood test reports to measure their levels. Every lab utilizes different equipment, which affects IgG test results. Choose Redcliffe Labs as your diagnostic partner for the IgG test. We offer the IgG test price at INR 390 to monitor your IgG levels.

Our phlebotomists will visit your home to collect samples. They will find a vein, clear the site, and insert a sterile syringe to collect blood samples. After collecting the samples, they will transfer them to the lab for testing. You will receive the IgG test reports within 15 hours. 

Risks Associated with IgG Test 

During the IgG blood test, the phlebotomist cleans the site with an alcoholic substance to prevent risks of infection. However, you may experience skin infection, hematoma, slight pain, bleeding, weakness, fatigue, or nausea. These signs won’t last long. They will disappear within a couple of minutes. If they last, seek a medical consultation. 

Understanding the IgG Test Results 

The IgG test shows whether immunoglobulin G levels are normal, low, or high. If the IgG level falls in the normal range (listed below), there is no deficiency of IgG in your blood. Still, your doctor may suggest other tests, such as a Complete Blood Count (CBC). 

Normal Range of IgG 

The IgG levels vary with age. Research shows that IgG levels are high during the newborn period, which eventually decreases for several months. Around 18 years of age, the IgG levels begin to rise. Have a look at the normal range of IgG as per age. 

IgG Levels during Pregnancy 

IgG levels in pregnant women tend to decrease in all three trimesters. 

Cause of High Immunoglobulin G Levels: 

Increasing polyclonal and monoclonal immunoglobulins is the major cause of high immunoglobulin G levels. The polyclonal increase can happen in any of the three immunoglobulins (IgG, IgM, and IgA), while the monoclonal increase in one, without a decrease in the other two classes. The reason include: 

• Allergies 
• Inflammatory bowel disease
• Cancer such as lymphoma, leukemia, or multiple myeloma
• Liver disease
• Autoimmune disorder (celiac disease, lupus, rheumatoid arthritis) 
• Acute or chronic infections 
• Cirrhosis 
• Chronic inflammation 
• Hyperimmunization reactions 
• Wiskott-aldrich syndrome 
• Infection during pregnancy, especially in a newborn
• Chronic lymphocytic leukemia 
• Waldenstrom’s macroglobulinemia (IgM) 
• Monoclonal gammopathy of undetermined significance (MGUS) 

Cause of Low Immunoglobulin G Levels: 

Low IgG levels can be caused by an underlying condition that may affect the production of immunoglobulins and increase protein deficiency in the body. Medical drugs are a major reason for low IgG levels. 

• Kidney disease 
• Weak immune system 
• Hereditary 
• Diabetes or prediabetic complications 
• Certain medicines (steroids) 
• Drugs (phenytoin, carbamazepine, immunosuppressant) 
• Delay in transient in the newborns 
• Nephrotic syndrome 
• Burns 
• Dysfunction in the gastrointestinal tract may affect digestion and absorption of protein. 

Factors that can affect IgG Test Results 

Factors that can affect IgG test results are: 

• Unhealthy lifestyles (alcohol consumption and sleep deprivation) 
• High BMI 
• Autoimmune disorder 
• Chronic infection 
• Stress 
• Relaxation techniques 
• Dehydration 
• Medications 
• Vaccines and nutrition

Treatment For IgG Deficiency

The IgG test, which helps detect the level of IgG antibodies in the blood, costs INR 390. Treatment for IgG deficiency completely depends on symptoms, causes, and infections. 

Initially, there are no symptoms, but as soon as they appear, it can lead to severe health problems and infections. If you have symptoms of diseases, treat them well with immunoglobulin therapy. 

Immunoglobulin therapy is an antibiotic treatment that helps boost your body’s immune system. It can prevent severe infections and sickness and reduce symptoms. The right care, regular testing, and follow-ups can be in early treatment. 

Do You Need Another Test After the IgG Test?

Follow-up tests help understand the situation completely. It doesn’t matter whether you have high, low, or normal IgG levels. Your healthcare provider may recommend a vaccine for a strong immune system. Vaccines such as polio or measles prevent immunoglobulin infections or diseases. 

Every laboratory uses different measuring techniques. Some might provide negative results, which is another reason to need a follow-up or another test. 

Some people have asymptomatic IgG deficiency, which makes it difficult to identify and detect IgG abnormalities. However, the immunoglobulin test can help measure subclass infection. 

Book the IgG Test @ INR 390! 

Immunoglobulin G is an essential antibody your immune system produces to fight against infections, germs, and illness. Every lab offers different prices because of the location, equipment, and methods. Redcliffe Labs believes in providing an IgG test to every Indian. We are present all over India with a home sample collection service. The IgG test price is INR 390, making the test both affordable and accessible for everyone. 

Immunoglobulin G (IgG) Test Cost in Different Cities - Redcliffe Labs

Note: We also offer Immunoglobulin G (IgG) Test PAN India. Please call the number 8988988787 to check the availability of our services in your area.

Why Book The IgG Test From Redcliffe Labs? 

Redcliffe Labs is a purpose-driver omnichannel service provider. Every citizen of India deserves a quality diagnosis. Our team goes through 50+ internal and external quality checks regularly. We are present in 220+ cities with over 2000 collection centers. All our labs follow NABL and ISO guidelines. Over 50,000 doctors trust us. That’s not it. 

Our phlebotomists are DMLT-certified. On every test worth INR 999, you can get a free personalized diet plan, report consultation, and health progress report. Our lab technicians follow the Six Sigma process to ensure 100% report correctness. So, what’s stopping you from booking the IgG test from us? Book the IgG test from India’s trusted lab!