IGG4 Test - Price, Purpose, Procedure, Results, & More

Table of Content

Introduction to IgG4 Test

Your body produces antibodies to fight against infections and germs. Antibodies in your immune system attach to antigens (fungi, bacteria, viruses, and certain toxins), which are removed. Whenever antigens (foreign substances) enter your body, antibodies recognize and attack them. There are five types of antibodies: IgA, IgD, IgE, IgG, and IgM. 

IgG is a common antibody that covers approximately 70% of the immunoglobulins in the body. It is found in tissues and blood and protects the body from viral and bacterial infections. IgG has four subclasses: IgG1, IgG2, IgG3, and IgG4. IgG4 is a type of antibody with anti-inflammatory properties. Its deficiency may cause autoimmune and respiratory infections. An IgG4 test may help detect the abnormality. Immunoglobulin G4 test is IgG4 test full form. 

If you have certain respiratory issues, it is better to consult a healthcare professional. They suggest an IgG4 blood test. Get it from Redcliffe Labs, a PAN-India Diagnostic Lab offering affordable test prices. The IgG4 test price is INR 7000. 

Test Details in Brief 

What is the Purpose of the IgG4 Test?

IgG4 is a rare disease affecting IgG4, 0.28 to 1.08 cases per 100,000 people. It is a subclass of IgG antibodies. The main purpose of the IgG4 test is to detect any abnormality present in the IgG antibody in the blood. High or abnormal IgG4 causes infection in the blood and sclerosing inflammation. The test also checks for: 

• Various antigens may lead to chronic infection. 
• High or low levels of IgG4 antibody. 
• Any IgG4-related diseases. 
• The overall functioning of the immune system. 

What Does The IgG4 Test Measure?

The IgG4 test measures the level of IgG4 antibodies in the blood. Doctors may prescribe the test if they see any abnormality. The test can also measure: 

• Certain medical conditions related to IgG abnormalities. 
• Levels of IgG4 antibodies in the blood. 
• The functioning of autoimmune disorders. 
• Antigens, germs, infections, and allergic reactions in the body. 
• A specific allergen triggers an allergic reaction. 
• The overall functioning of the immune system. 
• Your immune system’s response to a certain infection. 

IgG4 Disease Symptoms 

IgG is an antibody that protects against germs, illnesses, and diseases. IgG4 may cause several symptoms; some may be common, while some may be rare. These are: 

• Bulging eyes 
• Pain or redness in the eyes 
• Loss of eyesight
• Lumps or rashes 
• Enlargement of salivary glands 
• Back pain 
• Dry mouth 
• Unnecessary weight loss 
• Severe headaches
• Swollen lymph nodes 
• Kidney pain 
• Abdominal pain 
• Dry mouth 

Why Do You Need The IgG4 test?

Symptoms are one reason you need the IgG4 blood test, but there are certain other reasons as well.

• Autoimmune disorders- Medical conditions such as systemic lupus erythematosus (SLE), rheumatoid arthritis, and Sjogren's syndrome are some reasons why you should take the IgG4 test.
• Certain Allergic Reaction- Allergens may cause allergic reactions. If you experience one, such as food allergy, allergic asthma, or pollen allergy, take the IgG4 test. 
• Suspected Signs of IgG4-Related Diseases- Signs like respiratory issues are common during abnormal IgG4. The IgG4 test may help in the early detection and suspension of these disorders or diseases. 
• Signs of Tumor- If your doctor suspects signs of a tumor, they might recommend the IgG4 blood test. 
• Severe Inflammation- Take the IgG test for chronic pancreatitis and inflammation signs. 

Organs Affected By Abnormal IgG4 

IgG4 is a subclass of IgG antibody. Any abnormality can affect the body’s functioning. It can leave certain (above-listed) symptoms but may also affect certain organs. 

• Pancreas and Bile duct- IgG4 may cause acute pancreatitis, which may lead to abdominal pain and nausea. It may also cause jaundice. Some people may also experience irregular bowel movements, such as gas, constipation, diarrhea, weight loss, diabetes, and undernutrition. 
• Salivary and Lacrimal Glands- Abnormal IgG4 may cause painless and noticeable swelling on both sides of the face, chin, and upper eyelids. 
• Lungs: IgG4 may affect the lungs and cause cough, shortness of breath, pain while inhaling, and inflammation of the chest wall. 
• Orbit: IgG4 may affect the eye muscles, cause pain while rotating the eyes, and cause swelling or pain around the eyes. 

Causes of IgG4 

IgG4 is a rare disease; however, any abnormality may cause severe diseases. The IgG4 test may help detect abnormal levels of IgG4 and provide the right treatment. The IgG4 may cause: 

• Milkulicz’s disease 
• Kuttner’s tumor
• Eosinophilic Anglocentric fibrosis 
• Riedel’s thyroiditis 
• Idiopathic cervical fibrosis 
• Pulmonary inflammatory pseudotumor 
• Chronic sclerosing aortitis 
• Preaortitis and periarteritis 
• Autoimmune pancreatitis 
• Sclerosing cholangitis 
• Retroperitoneal fibrosis 
• Idiopathic tubulointerstitial nephritis 
• Sclerosing mesenteritis 
• Inflammatory aortic aneurysm 
• Multifocal fibrosclerosis 

IgG4 abnormality may lead to these chronic medical conditions. It is advisable to get tested before and take preventive measures. You can book the IgG4 test from Redcliffe Labs. We offer a home sample collection service, where our phlebotomists will visit your home to collect samples. It takes just a minute to book the test. 

How To Book The IgG4 Test From Redcliffe Labs?

Redcliffe Labs offers quality diagnostic services to people across India. We provide a reasonable home sample collection service, making it affordable and accessible for everyone. You can book the test either from our website or mobile app. The procedure is the same for both. You can also visit our lab to get tested; we have 80+ owned advanced labs. 

On your browser, search for ‘Redcliffe Labs near me.’ You will find our nearest lab. 

• Locate the address and visit the lab.
• You will meet our phlebotomist to collect blood samples. 
• Register and get yourself tested. 
• They are expert in conducting a seamless blood sample collection. 

Book the test from our ‘website’ or ‘mobile app.’ 

• Search for ‘Redcliffe Labs’ to find our website. Then, download our app to either the Play Store or the App Store. 
• On the home page, you will find a ‘book a test’ column; simply click on it. 
• You can book any test you wish; we have 3600+ tests. 
• Search for ‘IgG4 test’, add to the cart, fill in your details, and book the test. 
• In your chosen (preferred) slot, our phlebotomists will visit your home for sample collection. 
• Our DMLT-certified phlebotomist will transfer the sample to the lab for analysis. 
• You will receive your IgG4 test reports within the decided time. 

Preparation For The IgG4 Test 

The IgG4 test monitors the level of IgG4 antibodies in the blood. They are a core part of controlling the immune system, and your doctor can monitor its functioning by looking at the IgG4 test reports. The IgG4 blood test needs no special preparation. However, it requires a blood sample, which may make you feel weak or dizzy, so you should follow these guidelines before the test for correct reports. 

• Have a regular diet and avoid it only if asked by your doctor. 
• Keep your water level intake normal. Drink 8 glasses of water daily, 
• Avoid taking excessive stress before the test. 
• Clear all your doubts prior. 
• Practice deep-breathing exercises like yoga and meditation. 
• Don’t get up too fast from the bed on the day of testing. 
• Keep your mind calm. 
• Avoid wearing full-sleeved t-shirts.

IgG4 Test Procedure 

Once you have booked the test, our phlebotomists will arrive at your house to collect the sample. They are DMLT-certified to conduct a smooth blood sample collection procedure, which takes a couple of minutes and has no or minor side effects. 

• Tie an adhesive tape on your upper arm to locate an appropriate vein. 
• In some rare cases, they might collect blood from the wrist area. 
• After locating, they will clear the site with an alcoholic substance to prevent infections. 
• Insert a sterile syringe to collect blood samples. 
• They will transfer sufficient collected blood samples to a container. 
• They will put a cotton ball on the punctured site to prevent bleeding (for a couple of seconds). 
• Label the container with your details. 
• Once done, they will store the sample in a temperature-controlled bag and transfer it for testing. 
• That’s it. 
• You’re done with the test. Now, wait at least 3 days for the IgG4 blood test reports. 

Risks Associated With The IgG4 Test 

Our phlebotomists ensure that we avoid every possible risk. However, they have to insert a syringe to collect blood samples, which may cause a situation of: 

• Excessive blood loss
• Weakness 
• Skin infection
• Hematoma 
• Dizziness 
• Slight pain 
• Numbness or tingling in the hands and feet 
• Several punctures 

Understanding IgG4 Test Results 

The IgG4 test results help detect autoimmune pancreatitis and determine the type of AIP, undiagnosed cancer, abnormal levels of IgG4, and certain autoimmune disorders. The IgG4 level is different in every age. Here is the IgG4 normal range 

IgG4 Normal Range As Per Age 

Mg- milligrams & dL- deciliter

If your reports show a number above or below the above-referred range, you may be underlined with an abnormal IgG4. What happens when IgG4 is High? A high level of IgG4 may indicate: 

• Allergic disorder 
• Chrug-strauss syndorme 
• Sarcoidosis 
• Multicentric Castleman diseases

Risks Affecting The IgG4 Test Results 

• Location 
• Age 
• Gender 
• Medical diagnosis process 
• Smoking 
• Allergic reaction because of dust, vapors, or gases 

IgG4 Disease Treatment 

Corticosteroids, rituximab, and surgery (in some cases) can be used to treat IgG4-related disease. All treatments aim to prevent inflammation and the effects of IgG4 disorder. 

Rituximab is a medication that improves the immune system. Doctors usually prescribe it when they detect abnormalities in corticosteroids or recurrence of tapering. It is an effective treatment for IgG4. 

In some cases, doctors get ahead with surgeries such as stenting to release ureter blockage or bile ducts. Usually, organs return to normal functioning within a few days after the treatment. 

IgG4 Test Price @ Redcliffe Labs

The IgG4 test price is INR 7000 at Redcliffe Labs. We aim to provide quality diagnosis to every Indian. Our services are available across India. We offer a home sample collection service at affordable prices. Our labs regularly undergo 50 internal and external quality control checks to ensure accurate reports. We have over 500 dedicated riders providing the shortest TAT. With every test worth INR 999, you can avail of the value benefit of a personalized diet plan, health checkup, and report consultation. 

IgG 4 Test Cost in Different Cities - Redcliffe Labs

Note: We also offer IgG 4 Test PAN India. Please call the number 8988988787 to check the availability of our services in your area.

Protect Your Immune System With Redcliffe Labs! 

Redcliffe Labs prioritizes every Indian’s health. We are a purpose-driven PAN India omnichannel service provider working progressively to provide India with its right to quality diagnostics. We are present in 220+ cities, 80+ labs, and over 2000 collection centers. We offer an affordable price and 100% report correctness. So, focus on your health, build your immune system, and take the IgG4 test from Redcliffe Labs.