C3 Test - Price, Purpose, Procedure, Need, Report, & More

Table of Content

Introduction to Complement Protein Concentration (C3) Test

Complement component 3, called C3, is an essential immune system protein. This protein plays a crucial role in the body's innate immunity and provides the first line of defense against diseases. The C3 blood test helps measure this protein's activity in your blood. 

However, your doctor may recommend the test to diagnose and treat autoimmune diseases. The test is also carried out to monitor the disease's progress.

A C3 complement blood test informs your healthcare provider about your immune system and helps determine how parts of it respond to harmful substances.

This can help your healthcare provider diagnose autoimmune disorders and other conditions. If your doctor has advised you to take the C3 test, book your appointment with Redcliffe Labs. You can book your test online using our app or can call our agents to book your test. Experience the best 

diagnostic services right from your home at cost-effective prices. Book your C3 test Today!

Test details in brief

What is the purpose of the Complement Protein Concentration (C3) Test

The Complement Protein Concentration (C3) Test measures the levels of complement protein C3 in the blood. Here is the purpose of the C3 test- 

• The Component C3 test detects if you have recurrent bacterial infections.
• The test also helps to identify the signs of an autoimmune disease like lupus.
• The test helps to detect if you have inflammation or edema without any cause.
• The test helps to identify autoimmune diseases like lupus (Systemic Lupus Erythematosus or SLE) and rheumatoid arthritis.
• The test assesses the proper functioning of the complement system, which is part of the immune response.
• The test helps identify certain bacterial infections that may activate or deplete C3 levels.
• The test determines if low C3 levels are related to inherited complement deficiencies.
• The test helps to evaluate diseases like membranoproliferative glomerulonephritis (MPGN) or lupus nephritis.
• On the other side, C3 protein levels may be high if you have inflammatory conditions like sarcoidosis, ulcerative colitis, or certain types of cancer. The test may also rise if you are responding to autoimmune therapies.

What Does the Ce3 Test Measure?

The test determines the concentration of C3 in the blood to assess whether it is within the normal range. 

The Complement C3 is an essential component of the complement system, which helps defend the body against infections, promotes inflammation, and clears damaged cells. Abnormal levels can indicate issues with immune function.

Also, the test helps to detect and monitor conditions such as

• Autoimmune diseases (e.g., lupus, rheumatoid arthritis) where C3 levels are often reduced. Kidney disorders, including glomerulonephritis or membranoproliferative glomerulonephritis.
• Infections where complement activation is occurring.
• Hereditary angioedema (linked to complement dysfunction).

Preparation for the Complement Protein Concentration (C3) Test

No special preparation is required for the complement protein concentration test. Here are some instructions you must check before taking the test-

• Fasting- No fasting is required before the C3 test.
• Medications—If you take any supplements or medications, consult your physician before taking the test, as some medications might impact your test results.

In addition, if you have any doubts about the test, consult your doctor and get them cleared before taking it. 

The procedure of the Complement Protein Concentration (C3) Test

The Complement Protein Concentration (C3) Test is a simple and minimally invasive blood test. Here's a step-by-step guide to the procedure:

• Your healthcare provider will clean the arm area with an antiseptic solution and tie a tourniquet around it to make the veins more visible and facilitate access.
• Next, your healthcare provider will insert a syringe into the vein and draw the blood in the test tube or vial. You might feel a little pinch or sting during the process, but this will get normal sometime. 
• Once the blood sample is collected, the syringe is removed, and a bandage or cotton swab is placed over the puncture site.
• You will be able to continue your normal activities immediately unless advised otherwise.
• While there is no risk of blood tests, some people might experience minor bruising or soreness at the puncture site, which is common and usually resolves independently.

After sample collection, the blood sample will be sent to the laboratory for analysis, and the reports will be provided within 48 hours of sample collection.

What do the Complement Protein Concentration (C3) Test reports indicate?

The complement C3 test result will be provided within 48 hours of sample collection. The result may depend on the person’s health history, age, and gender. 

• The normal range of the complement C3 test is 80 to 160 milligrams per deciliter.
• Low Complement Levels- If your complement protein C3 levels are low, you may have component C3 deficiency. People with C3 deficiency are at risk of developing immune diseases.

However, if your test results have low levels of other complement components, your results have acquired disease. For example, lower levels of C3 are a sign of lupus. Low complement activity may also be due to the following conditions:

• Cirrhosis
• Lupus
• Malnutrition
• Bacterial infections
• Hepatitis
• Hereditary angioedema
• Elevated C3 Complement Levels 
• Chronic Infections
• Kidney Diseases like membranoproliferative glomerulonephritis (MPGN) or lupus nephritis.
• Hereditary Deficiency 

High C3 Complement—A high C3 complement result means inflammation in the body. The inflammation may be due to ulcerative colitis or other acute diseases such as leukemia, sarcoma, or Hodgkin's Lymphoma.

However, elevated levels of Ce3 are not the main indication of cancer.

In addition, high C3 complement levels may be found in people with diabetes. Therefore, another Ce3 test is necessary to confirm the diagnosis. High C3 complements indicate the following condition-

• Acute Infections
• Chronic Inflammation
• Metabolic Disorders

Is there any risk of Complement C3 Test?

There is no such risk associated with the Component C3 blood, but there are some risks you must know before taking the blood test. These include the following:

• Lightheadedness
• Nausea
• Hematoma (blood clot)
• Infection at the injection site 
• Excessive bleeding

If you experience any of these, call your doctor right away.

Who Should Take the Complement Protein Concentration (C3) Test?

The Complement Protein Concentration (C3) Test is recommended for people experiencing symptoms or conditions involving the immune or complement system. Here are some people who should take the test-

• For people with autoimmune disorders, symptoms include fatigue, joint pain, skin rashes, or unexplained inflammation.
• Those with Signs of Chronic or Severe Infections
• Patients with Suspected Kidney Diseases, such as Glomerulonephritis, lupus nephritis, or other kidney conditions related to immune complex deposition.
• People Diagnosed with Complement deficiency
• People with Symptoms of Inflammatory Conditions

When Should You Consult a Doctor?

If you are experiencing any of the above symptoms or have a family history of immune disorders, consult your healthcare provider. They may recommend a C3 test as part of a broader diagnostic approach.

This test is crucial for diagnosing and managing immune, infectious, or inflammatory conditions early.

What are the common symptoms related to C3 components?

The common symptoms related to Component C3 deficiency are- 

Here are the symptoms of Low C3 levels

Autoimmune Disorders (Systemic Lupus Erythema

• Skin rashes
• Fever
• Weight Loss

Kidney Diseases (e.g., Glomerulonephritis, Lupus Nephritis)

• Swelling in the legs, ankles, or face
• Foamy or dark urine
• High blood pressure
• Frequent urination at night

Chronic Infections

• Recurrent infections (bacterial or viral)
• Delayed recovery from infections
• Fever or chills

Symptoms of High C3 Levels

Acute Infections (e.g., Bacterial Infections, Sepsis)

• Fever
• Chills and sweats
• Rapid heartbeat
• Increased white blood cell count
• Pain or swelling at the infection site

Inflammatory Diseases (e.g., Inflammatory Bowel Disease)

• Abdominal pain
• Diarrhea or constipation
• Joint pain and swelling
• Fatigue

Metabolic Conditions (e.g., Obesity, Metabolic Syndrome)

• Excess weight gain
• Difficulty losing weight
• Increased blood pressure and blood sugar levels

Complement Protein Concentration (C3) Test price at Redcliffe Labs

The C3 Test price at Redcliffe Labs is 700. You can book your test with us using the Redcliffe Labs app or by calling our customer agents. We have over 80+ labs across PAN India, 2000+ collection centers, and 1000+ certified sample collection experts. Our labs follow international quality protocols to provide 100% correct results.

We cover more than 3600+ tests covering all age groups. Fully automated machines with the latest technology ensure that the chances of errors are less than 3.4 in 10 lakhs. We are trusted by more than 50,000 doctors across India. With every test, value benefits worth INR 999/- including personalized diet plans, health progress reports, and free report consultation. What are you waiting for? Book your Component C3 test today!

Complement Protein Concentration (C3) Test Cost in Different Cities

Note: We also offer Complement Protein Concentration (C3) Test PAN India. Please call the number 8988988787 to check the availability of our services in your area.

Book Your Component C3 Test Today with Redcliffe Labs!

The Component C3 test is important to assess immune health and identify underlying conditions, including autoimmune disorders, chronic infections, and kidney diseases. The Ce3 test measures the C3 protein level, provides crucial insights into immune activity, and helps doctors diagnose and manage conditions effectively.

The test not only monitors disease progression but also evaluates treatment response. The C3 test plays a key role in maintaining overall health. 

Even if your levels fall outside the normal range, it doesn't automatically exhibit a health condition. 

If you experience symptoms like recurrent infections, inflammation, or signs of autoimmune disease, consult your healthcare provider. Your healthcare provider will review your test reports with you and may suggest additional tests.