Introduction to CD19, Flowcytometry Test

The CD19 Flow Cytometry Test is a blood test to analyze B lymphocytes (B cells) in the immune system. CD19 is a protein found on the surface of B cells which plays an important role in immune responses. This test is performed using flow cytometry, a technique that helps to identify and measure specific immune cells in blood or bone marrow samples.

This CD19 flow Cytometry test helps diagnose B-cell disorders, including leukemia, lymphoma, and immune deficiencies. However, if you have symptoms like frequent infections, fatigue, abnormal blood counts, or a family of B-cell disorders, your doctor may suggest this test to ensure early diagnosis and timely treatment. Consult your doctor and take the CD19 flow cytometry test with Redcliffe Labs. The professionals here will provide the best diagnostic experience at affordable prices.

Test details in brief

Purpose of the CD19, Flowcytometry Test

The key purpose of the CD19 Flowcytometry test is-

1. Diagnosis of B-cell Disorders- The CD19 Test helps to detect B-cell lymphomas and leukemias, like Acute Lymphoblastic Leukemia (ALL) and Chronic Lymphocytic Leukemia (CLL). 
2. Monitoring Immunodeficiencies- The test identifies primary immunodeficiencies, such as Common Variable Immunodeficiency (CVID) and X-linked Agammaglobulinemia (XLA). The test helps to evaluate antibody deficiencies in patients with recurrent infections.
3. Post-Treatment Monitoring- Monitors patients undergoing treatment for B-cell malignancies (e.g., chemotherapy, immunotherapy). Assesses minimal residual disease (MRD) to detect cancer relapse.
4. Evaluation before and After Bone Marrow Transplant: This determines B-cell engraftment and immune reconstitution post-transplant. 

Preparation for the CD19, Flowcytometry Test

The CD19 Flow Cytometry Test is performed on blood, bone marrow fluid, or other tissue samples to analyze B-cell populations. Here is the procedure for the test-

Blood sample collection—During blood sample collection, the healthcare provider draws blood from the vein of the arm. He first cleans the arm area with an antiseptic solution and then inserts a needle to collect the blood sample into a vial or tube. The sample is then labeled and sent to the laboratory for further analysis.

Bone marrow aspiration procedure- The patient lies on their side or stomach during the procedure. The hip bone area is cleaned and numbed with local anesthesia. A small amount of liquid bone marrow (aspirate) is collected into a syringe. The sample is collected in a sterile tube and sent for testing. A bandage is applied to the site.

What do the CD19 Flowcytometry Test reports indicate?

The CD19 Flow Cytometry test measures the percentage and absolute count of CD19 cells in the blood and bone marrow sample. The test results help to diagnose and monitor B-cell-related disorders, including leukemia, lymphoma, immunodeficiencies, and autoimmune diseases.

Normal CD19+ B-cell Levels- A normal percentage of CD19 B cells in the blood or bone marrow suggest a healthy immune system. 

• CD19 B-cells in blood: 5%–20% of total lymphocytes.
• Absolute CD19 count: 100–600 cells/µL. 
• No signs of B-cell malignancies, immunodeficiency, or abnormal immune response.

Increased CD19+ B-cell Levels

Higher-than-normal CD19+ B-cell levels mean:

• B-cell malignancies
• Chronic Lymphocytic Leukemia (CLL)
• Acute Lymphoblastic Leukemia (ALL)
• B-cell Non-Hodgkin’s Lymphoma (NHL)
• Rheumatoid Arthritis (RA)
• Systemic Lupus Erythematosus (SLE)

• In the post-infection recovery phase, B-cell production is increased.

Decreased CD19+ B-cell Levels

Lower-than-normal CD19+ B-cell counts mean:

• Primary Immunodeficiency Disorders
• Common Variable Immunodeficiency (CVID)
• X-linked Agammaglobulinemia (XLA).
• Advanced-stage chronic infections (e.g., HIV, tuberculosis)

Who should take the CD19 Flowcytometry Test?

The CD19 Flow Cytometry Test is recommended for individuals with suspected B-cell disorders, immune system dysfunctions, or those undergoing treatment for blood cancers.

• Patients with suspected lymphoma or leukemia.
• Individuals with frequent infections and suspected immunodeficiency.
• Those undergoing B-cell targeted therapies (e.g., Rituximab therapy).
• Patients needing post-transplant monitoring.
• Autoimmune disease patient with B-cell abnormalities
• Patient undergoing bone marrow transplant
• People with chronic or recurrent infections

If your doctor suspects B-cell cancers, immunodeficiencies, or autoimmune disorders. If you are undergoing or planning B-cell targeted therapies or a bone marrow transplant.

What are the common symptoms related to the disease?

Here are the common symptoms of B-cell Malignancies includes-

• Swollen lymph nodes
• Frequent infections 
• Night sweats and fever
• Weight loss
• Fatigue and weakness
• Easy bruising or bleeding
• Bone pain (multiple myeloma)

If you are noticing the above symptoms, consult your doctor. Early detection is key to managing blood cancers, immune disorders, and autoimmune diseases. If you have these symptoms, consult your doctor for further evaluation.

CD19, Flowcytometry Test price at Redcliffe Labs

The CD19 Flowcytometry Test cost at Redcliffe Labs is INR 2200. All our labs follow the highest quality standards as per NABL and ISO guidelines. We have 50+ internal and external quality control checks. 

Our experienced professional doctors are MD pathologists and technicians. The Six Sigma process is followed for 100% report correctness. The chances of errors are less than 3.4 in 10 lakhs. Fully automated machines with the latest technology. Trusted by more than 50,000 Doctors across India. Book your CD19 Flowcytometry test with Redcliffe Labs today!

CD19, Flowcytometry Test Price in Different Cities

Note: We also offer CD19, Flowcytometry Test PAN India. Please call the number 8988988787 to check the availability of our services in your area.

Book Your CD19 Flowcytometry Test With Redcliffe Labs

The CD19 Flow Cytometry Test is crucial for diagnosing and monitoring B-cell-related disorders, including blood cancers, immunodeficiency syndromes, and autoimmune diseases. 

This test is important for people with suspected leukemia, lymphoma, multiple myeloma, or recurrent infections. Additionally, it helps evaluate immune deficiencies such as X-linked Agammaglobulinemia (XLA) or Common Variable Immunodeficiency (CVID), which may lead to frequent infections due to low antibody production.

The CD19 test provides essential data on treatment efficacy and immune system recovery for patients undergoing B-cell-targeted therapy (e.g., Rituximab, CAR-T cell therapy) or bone marrow transplants. 

Booking your CD19 Flow Cytometry Test with Redcliffe Labs ensures accurate results, advanced diagnostic technology, and expert analysis. Prioritize your health today by scheduling this C19 Flowcytometry test with Redcliffe Labs to understand the insights into your immune system and overall health.