Adenosine Deaminase (ADA) Test - Price, Purpose, Range 2024

Table of Content

Introduction to ADA Test

The cells in our body produce an enzyme called adenosine deaminase (ADA). Adenosine deaminase helps activate lymphocytes - a type of White blood cells that fight infections. The adenosine deaminase test is a blood test that helps to detect the Mycobacterium tuberculosis infection in pleural fluid to detect Tuberculosis. The test helps diagnose conditions caused by tuberculosis bacteria by measuring the amount of ADA in the pleural fluid. The high levels of ADA in pleural fluid or cerebrospinal fluid indicate TB. The primary function of ADA is to keep the immune system developed and maintained. If you notice symptoms like chest pain, coughing, or difficulty breathing, these might be signs of Tuberculosis; consult your doctor and take an ADA blood test. You can choose Redcliffe Labs as your diagnostic partner to get the 

Adenosine Deaminase Test. Book your test online, and the phlebotomist will come to your home to collect the sample. 

Test details in brief

Purpose of the Adenosine Deaminase Test

The primary purpose of the Adenosine Deaminase (ADA) test is to assess the ADA enzyme level in blood. The purpose of the adenosine deaminase test is-

• Tuberculosis Diagnosis- The test is used to diagnose Tuberculosis where TB infection involves the pleura or the central nervous system. High adenosine deaminase levels in pleural fluid or cerebrospinal fluid show the risk of TB. 
• Identification of Lymphocytic pleural effusion- The test helps identify the cause of pleural effusion among those infected. High ADA levels may cause tuberculous pleural effusion and certain other infections. 
• Meningitis-The test helps to identify meningitis. If you are experiencing the symptoms of tuberculous or fungal meningitis, your doctor may recommend an ADA blood test. 

Preparation for the Adenosine Deaminase Test

Before taking the ADA test, always communicate with your healthcare provider and ask your doubts. While the test does not require any special preparation, here are some general guidelines you must follow:

• The ADA serum test does not require fasting.
• Inform your healthcare provider in advance about any medications or supplements you are taking, as it might affect your reports.
• Do not take excessive caffeine, which might affect your adenosine deaminase level.
• Do not smoke or drink alcohol.

The procedure of the Adenosine Deaminase Test

The ADA test is the blood test used to detect the ADA levels in the blood. During the procedure, the phlebotomist will take the blood sample. Before collecting the sample, the phlebotomist will tie a band on your arm, cleanse the site with an antiseptic solution, and then carefully insert a needle to withdraw the blood. You may experience minor discomfort, which is completely normal for such procedures. The procedure will take up to 5 minutes. After sample collection, a bandage will be applied to the puncture site to halt bleeding. The collected blood sample will be sent to a laboratory for comprehensive analysis.

What do the Adenosine Deaminase Test reports indicate?

The ADA blood test reports will be available within 12 hours of the ADA blood test. The interpretation of the ADA serum test will be as follows- 

• High ADA Levels- If the ADA level is high in the pleural fluid in a person with signs and symptoms, it might indicate Tuberculosis. However, if the person doesn't have Tuberculosis and the ADA level is still high, then it might be a reason for cancer (particularly lymphomas), pulmonary embolus, sarcoidosis, or lupus. High ADA levels in the blood might be associated with infections, inflammatory diseases, or certain cancers.
• Normal ADA Levels- The normal adenosine deaminase level does not mean you are not suspected of Tuberculosis or other infections. In some cases, Tuberculosis may have normal ADA levels, which can be confirmed after specific diagnostic tests.

The ADA test is a diagnostic tool, not a definitive diagnosis. The results should be discussed with a qualified healthcare professional who can consider the broader clinical context. 

What Is The ADA Normal Range?

The normal range of ADA levels in males and females is 40 units/L. If the ADA levels are above the normal range, it might indicate certain diseases. ADA levels above the normal range generally indicate various health conditions like Pleural Tuberculosis, Synovitis caused by rheumatoid arthritis, Pneumonia associated with Tuberculosis, Tubercular ascites, Meningitis of Tuberculosis, and Lymphadenitis of Tuberculosis. 

What if the Adenosine Deaminase Test reports are positive?

If the ADA test reports are positive, which means elevated levels of ADA, it might suggest the presence of health issues. The positive ADA serum test t-reports indicate-

• Tuberculosis- The positive ADA blood test reports indicate a tuberculous infection in pleural or cerebrospinal fluid. 
• Inflammatory conditions- Certain non-infectious inflammatory conditions, such as rheumatoid arthritis, may also cause an increase in adenosine deaminase levels.
• Infections- The high levels of ADA are associated with other infections that may affect the pleura or CNS.
• Cancers- In some cases, the high ADA levels may lead to certain cancers.

If your ADA levels are high and you find them positive, then consult your reports with your doctors. Your healthcare provider may recommend the proper treatment based on your test reports and medical evaluation. 

Who should take the Adenosine Deaminase Test?

The Adenosine Deaminase (ADA) test is recommended for people exhibiting symptoms. There are specific categories of people who might be at risk;

• People who are experiencing symptoms like chest pain or chronic cough
• Those who are susceptible to TB 
• Children
• People with weak immune system 
• HIV/AIDS patients
• Pregnant women
• Elderly people
• Organ Transplants recipients
• Diabetic and kidney disorder patients

Consult with your doctor about the symptoms and risk factors. Based on your clinical signs and medical history, your doctor may identify the need for an ADA test and will recommend ADA testing. 

What are the common symptoms related to abnormal ADA levels tests?

If you notice the below symptoms, then you must consider taking the ADA blood test- 

Tuberculosis (TB)

• Chest pain
• Chronic cough
• Heat and chills
• Skin rashes and allergies
• Pneumonia
• Sweating
• Fever
• Weight loss

Immunodeficiency Disorders (like Severe Combined Immunodeficiency - SCID)

•  Frequent and severe infections
•  Failure to thrive (especially in infants)
•  Recurrent respiratory infections
• Chronic diarrhoea
• Skin rashes

If you are experiencing symptoms, it is recommended that you consult with a healthcare provider for proper evaluation and diagnosis.

What is the risk of an ADA test?

The Adenosine Deaminase (ADA) test is generally safe with no or minimal risk. The test is a standard diagnostic blood test in which blood samples will be collected. The risk of the ADA blood test may be:

• Pain or discomfort- Some people might experience mild pain, discomfort, or bruising at the arm site.
• Infection- While rare, there is a minimal infection risk at the blood draw site. 
• Fainting or Dizziness- Some people may feel lightheaded or dizzy during or after the blood draw. 

Take the ADA test from Redcliffe Labs to avoid the risk during the blood collection. The professional phlebotomist follows standard procedure and takes precautions to ensure the well-being of people.

ADA Test price at Redcliffe Labs

The ADA test price at Redcliffe Labs is INR 599. You can book your test online with Redcliffe Labs. You need to call or visit our website to book your test. Our Labs are NABL-accredited and ISO-certified, so you do not need to worry about the reliability and accuracy of test reports. The phlebotomist will come to your home to collect the sample. Book your test with us to get the best diagnostics and hassle-free experience. Early diagnosis can help you to manage the ADA level and significantly improve your quality of life. Give us a call or schedule an ADA serum test with Redcliffe Labs in just 1 minute.

Conclusion

The ADA test is vital to assess and monitor specific health conditions, particularly Tuberculosis and immunodeficiency disorders. The test measures the adenosine deaminase level in the blood. 

Beyond tuberculosis and immunodeficiency disorders, the serum ADA test helps assess various inflammatory conditions, including peritonitis and certain lymphoid malignancies. Your healthcare provider may recommend the test based on clinical symptoms, medical history, and other diagnostic findings. For the best diagnostic services, take ADA blood tests from Redcliffe Labs at affordable prices. We ensure reliable and accurate results as our laboratories adhere to stringent quality control measures, ensuring precise measurements of Adenosine Deaminase levels. This can be crucial for accurately diagnosing conditions like tuberculosis or immunodeficiency disorders, guiding healthcare decisions, and facilitating timely interventions. Book your ADA test with us today!